Nutritional screening before heart surgery
Nutritional Screening in Patients With Cardiovascular Disease
Hull University Teaching Hospitals NHS Trust · NCT07409519
This project will test whether simple nutrition questionnaires, body measurements, and blood tests taken before heart surgery can help predict recovery time and complications in patients with cardiovascular disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 40 Years to 85 Years |
| Sex | All |
| Sponsor | Hull University Teaching Hospitals NHS Trust (other gov) |
| Locations | 1 site (Hull, E. Riding Yorkshire) |
| Trial ID | NCT07409519 on ClinicalTrials.gov |
What this trial studies
This is a cross-sectional preoperative study enrolling patients scheduled for cardiac surgery who can complete English-language questionnaires and provide consent. Investigators collect routine malnutrition tools (MUST, NRS), diet-quality measures (NOVA ultra-processed food intake, Mediterranean diet score), blood and urine biomarkers (including PNI and CONUT), grip strength, and detailed body composition (fat mass, fat-free mass, segmental analysis, visceral fat). Participants also complete questionnaires on sleep, recent physical activity, stress, anxiety, and depression. These measures will be linked to clinical outcomes such as mechanical ventilation time, ICU and hospital length of stay, and SCTS-defined complications to identify which nutritional screens predict poorer recovery.
Who should consider this trial
Good fit: Adults undergoing planned cardiac surgery at Hull University Teaching Hospitals who can read English and provide written consent are ideal candidates.
Not a fit: Patients who require emergency surgery or who cannot complete English-language questionnaires or provide consent are unlikely to benefit from this preoperative screening approach.
Why it matters
Potential benefit: If successful, the approach could help clinicians identify patients who need nutritional support before surgery to reduce complications and shorten ICU or hospital stays.
How similar studies have performed: Previous research has linked malnutrition scores and biomarkers with worse surgical outcomes, but combining detailed diet-quality measures and body composition in the preoperative setting is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: • No pre-specified inclusion criteria to ensure we recruit a representative group of patients. Exclusion Criteria: * All patients without proficiency in English that allows completion of questionnaires * Unable to provide written consent
Where this trial is running
Hull, E. Riding Yorkshire
- Hull University Teaching Hospitals NHS Trust — Hull, E. Riding Yorkshire, United Kingdom (RECRUITING)
Study contacts
- Study coordinator: Mahmoud M Loubani, MD
- Email: mahmoud.loubani@nhs.net
- Phone: +44 (1482) 624379
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiovascular Diseases, Nutrition, Screening, Cardiac surgery, Clincial outcomes