Nutritional program to improve cardiovascular health in women

Evaluation of Nutritional Prevention Program for Women's Cardiovascular Health on Quality of Life (SAFE)

Not applicable Interventional Institut Pasteur de Lille · NCT06380218

This study tests if a nutrition program using 'Primevère margarine' can help women aged 40 to 65 at risk for heart disease improve their health and quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages40 Years to 65 Years
SexFemale
SponsorInstitut Pasteur de Lille Academic / other
Locations1 site (Lille, Nord)
Trial IDNCT06380218 on ClinicalTrials.gov

What this trial studies

This study evaluates the impact of a nutritional prevention program that includes the consumption of 'Primevère margarine' on the quality of life of women aged 40 to 65 who are at risk for cardiovascular disease. Participants will attend 10 group coaching sessions focused on nutrition and physical activity, aiming to improve their eating habits and physical fitness. The program assesses various factors such as food balance, eating behavior, nutritional knowledge, and physical abilities to promote healthier lifestyles and enhance cardiovascular health.

Who should consider this trial

Good fit: Ideal candidates are women aged 40 to 65 with a BMI over 25 kg/m² or a waist circumference greater than 88 cm who regularly consume butter or standard margarine.

Not a fit: Patients who consume healthy margarine enriched with omega-3 or have serious chronic diseases may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly improve the quality of life and cardiovascular health of women at risk.

How similar studies have performed: Other studies have shown success with similar nutritional and lifestyle intervention approaches for improving cardiovascular health, indicating potential for positive outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* BMI \> 25kg/m² and/or with a waist circumference \> 88 cm
* Regularly consuming butter and/or "standard" margarine rich in saturated fatty acids

Exclusion Criteria:

* Regularly consuming "healthy" margarine enriched with omega 3 (Primevere, St Hubert ω3 ...) or with phytosterols (Pro-active)
* Consuming omega-3 rich food supplements within 3 months of inclusion
* Treated with lipid-lowering agents (statins), antidiabetic or antihypertensive drugs for less than 3 months
* Suffering of eating disorders
* Presenting a medical contraindication to the practice of physical activity
* Having previously participated in a similar prevention program
* Suffering from serious chronic diseases (cancer, serious cardiovascular history, etc.)

Where this trial is running

Lille, Nord

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy VolunteersNutritional and physical activity programPreventionCardiovascular healthQuality of life
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.