Nutritional management for cognitive symptoms after COVID-19

Nutritional Management of Post COVID-19 Cognitive Symptoms

Not applicable Interventional University of Alberta · NCT05705648

This study is testing whether taking medium chain triglyceride oil can help improve brain fog in people aged 22-50 who are dealing with long COVID symptoms.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages22 Years to 50 Years
SexAll
SponsorUniversity of Alberta Academic / other
Locations1 site (Edmonton, Alberta)
Trial IDNCT05705648 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to investigate cognitive complaints, often referred to as 'brain fog', in individuals aged 22-50 who have experienced long COVID. Participants will be randomly assigned to receive either medium chain triglyceride oil or safflower oil daily, and their cognitive function will be assessed through brain testing and questionnaires. The study seeks to determine the natural progression of these cognitive symptoms and the potential effects of the dietary oils on improving them.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 22-50 who have had a confirmed COVID-19 infection at least three months prior and are experiencing ongoing cognitive complaints.

Not a fit: Patients with pre-existing cognitive complaints or medical conditions affecting cognitive function may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective nutritional interventions for alleviating cognitive symptoms in long COVID patients.

How similar studies have performed: While there is ongoing research into cognitive symptoms post-COVID, this specific approach using nutritional oils is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* confirmed COVID infection, at least 3 months previously, with ongoing cognitive complaints
* all other medical conditions stable, and on stable doses of medications (if required)

Exclusion Criteria:

* COVID infection not confirmed by PCR or Rapid test
* unable to speak English
* pre-COVID cognitve complaints, and/or medical diagnoses affecting cognitive function

Where this trial is running

Edmonton, Alberta

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Long COVIDbrain fogconfusionmemory lossfunctional decline
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.