Nutrition management for infants undergoing heart surgery

A Multi-center Longitudinal Cohort Study on Peri-operative Nutrition in Infants With Congenital Heart Disease

Guangzhou Medical University · NCT03626480

This study is testing how managing nutrition before and after heart surgery can help infants with congenital heart disease recover better and improve their long-term health.

Quick facts

Study typeObservational
Enrollment20000 (estimated)
Ages1 Day to 12 Months
SexAll
SponsorGuangzhou Medical University (other)
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT03626480 on ClinicalTrials.gov

What this trial studies

This multi-center cohort study aims to monitor the peri-operative nutrition of infants diagnosed with congenital heart disease who are scheduled for surgery. Data will be collected at various intervals, including pre-surgery and at 1, 3, 6, and 12 months post-surgery, focusing on nutritional status, biochemical indices, and quality of life. The study seeks to understand the impact of nutritional management on recovery and long-term health outcomes in these children, addressing the challenges posed by surgery and potential malnutrition.

Who should consider this trial

Good fit: Ideal candidates for this study are infants under one year old diagnosed with congenital heart disease who are scheduled for surgical intervention.

Not a fit: Patients with chromosomal diseases, genetic metabolic disorders, or those with conditions affecting oral feeding may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve nutritional outcomes and overall recovery for infants with congenital heart disease undergoing surgery.

How similar studies have performed: While there is limited data on similar studies, the focus on peri-operative nutrition in this specific population is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All children in the multi-center who met the following criteria:

  1. under 1 years old (including 1 years old);
  2. diagnosed as congenital heart disease and planed to surgery;
  3. parents have basic literacy skills, communication and accessibility
  4. parents are informed consent and volunteered to participate with the approval of the hospital ethics committee,

Exclusion Criteria:

* (1) suspected as chromosomal disease; (2) diagnosis of genetic metabolic diseases; (3) anyway affecting oral feeding (eg. Cleft palate) (4) previous gastrointestinal surgery (eg. Postoperative gastrointestinal fistula)

Where this trial is running

Hangzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Congenital Heart Disease, Surgery, Nutritional outcome, Infants

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.