Nurse-led pre-op education with direct physiotherapy referral to reduce leakage after prostate removal
Official title: Pre-Operative Nurse-Led Education With Direct Physiotherapy Referral to Reduce Post-Prostatectomy Incontinence
Run by Royal College of Surgeons, Ireland · NCT07426861 · Data updated 2026-11-12
This project sees if a one-to-one nurse-led pre-operative education session plus automatic referral to supervised pelvic floor physiotherapy reduces urinary leakage in men having radical prostatectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 80 (estimated) |
| Sponsor | Royal College of Surgeons, Ireland Academic / other |
| Locations | 1 site (Beaumont, Dublin) |
| Status | Recruiting |
| Started | December 20, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2028 |
| Registry record updated | February 23, 2026 |
| Trial ID | NCT07426861 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Men aged 18 or older with prostate cancer who are scheduled for radical prostatectomy, can give informed consent, and have no pre-existing incontinence or contraindication to pelvic floor physiotherapy.
✕Probably not a fit
Patients with pre-existing urinary incontinence, prior pelvic radiotherapy or prior prostate surgery that affects continence, or medical contraindications to physiotherapy are unlikely to benefit from this pathway.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The PRO-ACT trial is a single-centre, parallel-group randomized controlled trial at Beaumont RCSI Cancer Centre that randomises men 1:1 to either standard care or a structured pre-operative bundle. The intervention includes a one-to-one advanced nurse practitioner education session, a scheduled 7–10 day post-operative telephone follow-up, and direct referral to supervised pelvic floor physiotherapy, while the control arm receives an educational video and patient-initiated referral. The primary outcome is mean urinary pad use per 24 hours at three months measured using a seven-day pad diary, with secondary outcomes including time to continence, EQ-5D-5L quality-of-life scores, physiotherapy uptake, and 90-day complications. Follow-up visits occur at six weeks and three months post-operatively.
Why it matters
Potential benefit: If successful, the intervention could shorten the time men take to regain continence after prostatectomy and improve post-operative quality of life.
How similar studies have gone: Pelvic floor muscle training has been shown in prior trials to improve post-prostatectomy continence, but structured pre-operative nurse-led education with automatic physiotherapy referral has been less extensively studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Male patients aged ≥ 18 years Diagnosis of prostate cancer Scheduled for radical prostatectomy (open, laparoscopic, or robotic-assisted) Able to provide written informed consent Exclusion Criteria: Pre-existing urinary incontinence requiring pad use Prior pelvic radiotherapy Prior prostate surgery affecting continence outcomes Medical contraindication to participation in pelvic floor physiotherapy Inability to provide informed consent
Where it's running
-
Beaumont RCSI Cancer Centre
Beaumont, Dublin, Ireland Recruiting
Study contacts
- Study coordinator: Sara White
- Email: sarawhite@beaumont.ie
- Phone: +35318093000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Rehabilitation and Sex Therapy to Improve Recovery After Prostate Cancer Treatment
This study tests whether adding telehealth sex therapy to pelvic floor physical therapy helps men recover sexual function after prostate cancer treatment.
-
Testing REGN5678 in high-risk localized prostate cancer before surgery
This study is testing a new drug called REGN5678 in men with high-risk localized prostate cancer to see if it can help them before they have surgery.
-
Laser therapy for prostate cancer treatment
This study is testing a new laser treatment for men aged 50 to 80 with low to intermediate risk prostate cancer to see if it is a safer and less invasive option than traditional surgery or radiation.
-
Focal therapy using high-intensity focused ultrasound for prostate cancer
This study is testing whether high-intensity focused ultrasound can effectively treat localized prostate cancer while causing fewer side effects compared to standard treatments.
-
Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery
Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.
-
Targeted alpha therapy for B7-H3 expressing solid tumors using AKY-2519
This phase 1b trial tests a radiolabeled drug (AKY-2519) to see if it's safe and tolerable in adults with B7-H3 positive advanced solid tumors, including NSCLC and SCLC, with imaging to help guide use.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.