NPC Screening Cohort in South China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort aims to create a large, integrated dataset and biobank to study NPC risk factors and early detection methods. Participants provide epidemiological information and biological samples, which are analyzed for EBV markers, genetic information, and other risk indicators. Those flagged as high-risk undergo confirmatory clinical imaging and nasopharyngoscopy to identify NPC, with long-term follow-up to understand risk factors and molecular mechanisms. The study intends to establish a scalable screening strategy across multiple centers in South China, starting with high-incidence regions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Residents with a definite native place;
* Aged 30 and 69 years at screening;
* Capable of long-term cooperation with screening and follow-up.

Exclusion Criteria:

* Known severe cardiovascular, liver or kidney disease, or neuropsychiatric disorders;
* History of previous malignant tumors;
* Severe autoimmune diseases or immunodeficiency;
* Females with a positive pregnancy test at screening;
* Inability to cooperate with the study due to psychological, social, family, and geographical reasons.

Where it's running

• The Fifth Affiliated Hospital of Sun Yat-sen University
  Zhuhai, Guangdong, China Recruiting

Study contacts

• Study coordinator: Ming-yuan Chen, MD, PhD
• Email: chmingy@mail.sysu.edu.cn
• Phone: 86-13903052650

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.