Noninvasive neuromodulation for people with traumatic brain injury and healthy volunteers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, double-blind Phase 2 trial, patients with diffuse axonal injury and healthy volunteers are assigned to active or sham REAC after ICU discharge. The intervention includes one Neuro Postural Optimization session followed by up to 18 NPPO-BWO-G sessions (maximum four per day), for a total of 19 sessions. Quantitative EEG (qEEG) and population brain electrical mapping will measure cerebral electrical activity before and after the protocol. The trial compares qEEG pattern changes between active and sham groups to determine whether REAC alters brain wave activity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* DAI diagnostic and consent for participation with the next of kin for each eligible patient

Exclusion Criteria:

* Open TBI
* History of chronic neurological conditions

Where it's running

• Hospital das Clínicas da FM-USP
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: Sérgio Brasil, MD. PhD.
• Email: sbrasil@alumni.usp.br
• Phone: +5511981210990

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.