Noninvasive brain stimulation for treating amblyopia in adults
Multi-day Effect of Noninvasive Brain Stimulation in Adults With Amblyopia
This study is testing a new non-invasive brain stimulation method to see if it can help adults with amblyopia improve their vision.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | Midwestern University Academic / other |
| Locations | 1 site (Downers Grove, Illinois) |
| Trial ID | NCT06712849 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of non-invasive brain stimulation, specifically high-frequency transcranial random noise stimulation, in treating adults with amblyopia. Participants will be randomly assigned to receive either active stimulation or sham stimulation over five consecutive days. The study aims to assess the impact of this intervention on neuronal plasticity in the visual cortex and its effects on visual perception and function. Researchers will measure various visual acuity parameters to evaluate the outcomes of the treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 55 with a formal diagnosis of amblyopia.
Not a fit: Patients with a history of optic nerve disease, neurological conditions, or those with metal/electronic implants may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve visual perception and function in adults suffering from amblyopia.
How similar studies have performed: While the approach of using non-invasive brain stimulation is relatively novel in the context of adult amblyopia, similar techniques have shown promise in other neurological and visual disorders.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults between 18 and 55 years of age * Formal diagnosis of amblyopia in one or both eyes of any etiology Exclusion Criteria: * History of optic nerve disease, including glaucoma and optic neuritis * History of neurological conditions, including demyelinating disease or stroke * Presence of metal or electronic implants in or on the body, including pacemakers * Taking medications that can affect normal neurological function, including antipsychotics, antiepileptics, and opioids
Where this trial is running
Downers Grove, Illinois
- Midwestern University Eye Institute — Downers Grove, Illinois, United States (Recruiting)
Study contacts
- Study coordinator: Arijit Chakraborty, PhD
- Email: achakr@midwestern.edu
- Phone: 630-960-3172
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.