Clinical trial Recruiting at 1 site Interventional Ages 18 to 99

Non-surgical treatment for gum disease around dental implants

Official title: A Comparison of Two Different Mechanical Interventions in Non-Surgical Peri-implantitis Treatment

Run by Kutahya Health Sciences University · NCT06514677 · Data updated 2026-11-12

This study is testing two different non-surgical treatments for gum disease around dental implants to see which one works better for patients with this condition.

More Peri-implantitis trials

Quick facts

Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment60 (estimated)
SponsorKutahya Health Sciences University
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Kütahya)
StatusRecruiting
StartedDecember 1, 2023
Main results expectedMay 1, 2025
Study endsDecember 1, 2025
Registry record updatedMarch 12, 2025
Trial IDNCT06514677 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with mild to moderate peri-implantitis and systemically healthy status.

Probably not a fit

Patients with severe peri-implantitis, mobile implants, or those with active periodontal disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of two different non-surgical treatments for peri-implantitis, a condition affecting dental implants. A total of 60 patients with mild to moderate peri-implantitis will be randomly assigned to receive either ultrasonic carbon tip debridement or titanium curette treatment. Clinical parameters such as bleeding on probing, probing pocket depth, and radiographic bone levels will be assessed at multiple time points over a year to determine the efficacy of each treatment method. The study seeks to provide insights into the best non-surgical approach for managing this common dental complication.

Why it matters

Potential benefit: If successful, this study could lead to improved non-surgical treatment options for patients suffering from peri-implantitis, potentially preserving their dental implants.

How similar studies have gone: Previous studies have shown promising results with non-surgical treatments for peri-implantitis, indicating that this approach is both viable and potentially effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

1. Adult patients (≥18 years old)
2. Systemically healthy (ASA class 1 and ASA class 2)
3. Full-mouth plaque scores ≤20%
4. Implant had been in function for more than 6 months
5. Absence of plaque around the implant
6. Consent to complete all follow-up visits

Exclusion criteria:

1. Mobile implant
2. Overhanging restorations that prevent access to the implant for clinical measurements
3. Unresolvable technical complications that can cause peri-implantitis
4. Presence of active periodontal disease
5. Implants with a history of peri-implantitis treated using graft materials
6. Use of drugs that cause gingival hyperplasia
7. Systemic antibiotic use in the last 3 months
8. Acute and chronic medical conditions that prevent the patient from participating in the study
9. Presence of uncontrolled severe peri-implantitis from neighbouring implants
10. History of radiotherapy in the head and neck region
11. Receiving acute chemotherapy
12. Current corticosteroid therapy

Where it's running

  • Kütahya Health Sciences University Faculty of Dentistry, Department of Periodontology
    Kütahya, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.