Non-surgical treatment for gum disease around dental implants

A Comparison of Two Different Mechanical Interventions in Non-Surgical Peri-implantitis Treatment

NA · Kutahya Health Sciences University · NCT06514677

This study is testing two different non-surgical treatments for gum disease around dental implants to see which one works better for patients with this condition.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorKutahya Health Sciences University (other)
Drugs / interventionschemotherapy
Locations1 site (Kütahya)
Trial IDNCT06514677 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of two different non-surgical treatments for peri-implantitis, a condition affecting dental implants. A total of 60 patients with mild to moderate peri-implantitis will be randomly assigned to receive either ultrasonic carbon tip debridement or titanium curette treatment. Clinical parameters such as bleeding on probing, probing pocket depth, and radiographic bone levels will be assessed at multiple time points over a year to determine the efficacy of each treatment method. The study seeks to provide insights into the best non-surgical approach for managing this common dental complication.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with mild to moderate peri-implantitis and systemically healthy status.

Not a fit: Patients with severe peri-implantitis, mobile implants, or those with active periodontal disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved non-surgical treatment options for patients suffering from peri-implantitis, potentially preserving their dental implants.

How similar studies have performed: Previous studies have shown promising results with non-surgical treatments for peri-implantitis, indicating that this approach is both viable and potentially effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

1. Adult patients (≥18 years old)
2. Systemically healthy (ASA class 1 and ASA class 2)
3. Full-mouth plaque scores ≤20%
4. Implant had been in function for more than 6 months
5. Absence of plaque around the implant
6. Consent to complete all follow-up visits

Exclusion criteria:

1. Mobile implant
2. Overhanging restorations that prevent access to the implant for clinical measurements
3. Unresolvable technical complications that can cause peri-implantitis
4. Presence of active periodontal disease
5. Implants with a history of peri-implantitis treated using graft materials
6. Use of drugs that cause gingival hyperplasia
7. Systemic antibiotic use in the last 3 months
8. Acute and chronic medical conditions that prevent the patient from participating in the study
9. Presence of uncontrolled severe peri-implantitis from neighbouring implants
10. History of radiotherapy in the head and neck region
11. Receiving acute chemotherapy
12. Current corticosteroid therapy

Where this trial is running

Kütahya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Peri-Implantitis, Alveolar Bone Loss

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.