Non-surgical rehabilitation for ACL injuries
Official title: Rehabilitation Treatment of Anterior Cruciate Ligament Rupture
Run by Aarhus University Hospital · NCT04408885 · Data updated 2026-11-12
This study tests a non-surgical rehab program for people with ACL injuries to see how well it helps them recover and whether they still need surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Aarhus University Hospital Academic / other |
| Locations | 1 site (Aarhus N) |
| Status | Recruiting |
| Started | August 15, 2020 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2030 |
| Registry record updated | October 1, 2025 |
| Trial ID | NCT04408885 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals diagnosed with an ACL injury who have chosen rehabilitation as their treatment method.
✕Probably not a fit
Patients with other knee ligament instabilities, rheumatoid arthritis, or Morbus Bechterews Disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of a non-surgical rehabilitation program for patients with anterior cruciate ligament (ACL) injuries. It aims to assess patient-reported outcomes, functional levels, and the rate at which patients opt for surgical treatment. The study will collect data on the effectiveness of rehabilitation as a treatment option for ACL injuries. Participants will be monitored throughout their rehabilitation process to evaluate their progress and outcomes.
Why it matters
Potential benefit: If successful, this approach could provide an effective non-surgical treatment option for patients with ACL injuries.
How similar studies have gone: Other studies have shown promising results for non-surgical rehabilitation approaches in managing ACL injuries, indicating potential for success in this study.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Anterior cruciate ligament injury where rehabilitation regime is selected as treatment. Exclusion Criteria: * Other knee ligament instability * Rheumatoid arthritis * Morbus Bechterews Disease
Where it's running
-
Division of Sports Trauma, Palle Juul-Jensens Boulevard 99
Aarhus N, Denmark Recruiting
Study contacts
- Study coordinator: Torsten G Nielsen, PT
- Email: torsne@rm.dk
- Phone: +4540491184
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Motor imagery–enhanced rehab after ACL reconstruction
This study tests whether mentally practicing movement can improve knee function and brain activity after ACL reconstruction, in comparison with standard rehab.
-
Functional Movement Training vs Functional Stability Training after ACL Surgery
This randomized trial tests whether a functional movement program or a stability-focused program helps 18-35 year old athletes recover after ACL surgery.
-
Intraoperative Energy Use During ACL Surgery
This study tests how much workload a surgeon experiences during ACL reconstruction procedures while wearing a Hexoskin shirt.
-
Differences in Outcomes After Allograft vs Autograft in Revision ACL Repair
This study looks at whether using donor tissue (allograft) versus the patient’s own tissue (autograft) in revision ACL surgery leads to different results.
-
Functional brain signal changes after ACL reconstruction with targeted neuromotor training
This project will test whether targeted neuromotor training after ACL reconstruction changes brain activity patterns in active adults aged 18–30.
-
Assessing ACL injury risk in healthy athletes
This study is trying to see how muscle strength and movement patterns in healthy athletes can help predict the risk of ACL injuries over a year.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.