Non-narcotic pain control after ACL surgery
Non-Narcotic Pain Control After ACL Reconstruction
This study is testing whether a non-narcotic pain medication called ketorolac can help people manage pain after ACL surgery just as well as the narcotic oxycodone.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 15 Years to 55 Years |
| Sex | All |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 3 sites (Coral Springs, Florida and 2 other locations) |
| Trial ID | NCT06973785 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of oral ketorolac compared to oral oxycodone for pain management following anterior cruciate ligament (ACL) reconstruction surgery. It is a double-blind, randomized controlled trial involving two groups of patients, where one group receives ketorolac and the other receives oxycodone. The study aims to reduce the reliance on narcotics by documenting the number of patients who do not use any narcotics post-surgery. Participants will be monitored for their pain management needs and medication usage in the first 72 hours after surgery.
Who should consider this trial
Good fit: Ideal candidates are males and females aged 15-55 who are undergoing primary autograft ACL surgery.
Not a fit: Patients who are not undergoing ACL reconstruction or those outside the age range of 15-55 may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a safer pain management alternative that minimizes narcotic use after ACL surgery.
How similar studies have performed: Previous studies have shown promising results in reducing narcotic use with non-narcotic pain management strategies, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or female, aged 15-55 years * Primary Autograft ACL surgery * Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts Exclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for t the duration of the study * Male or female, aged 15-55 years * Primary Autograft ACL surgery * Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts
Where this trial is running
Coral Springs, Florida and 2 other locations
- Cleveland Clinic Coral Springs — Coral Springs, Florida, United States (Active_not_recruiting)
- Cleveland clinic sports medicine — Garfield, Ohio, United States (Recruiting)
- Cleveland Clinic — Strongsville, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Kurt P Spindler, MD — The Cleveland Clinic
- Study coordinator: Jennifer Baldwin
- Email: baldwij3@ccf.org
- Phone: 216.390.5833
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.