Non-invasive urine and stool tests for early colorectal cancer diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to identify specific metabolites in urine and stool samples that can differentiate between patients with colorectal cancer or polyps and healthy individuals. By utilizing metabolomics techniques, the study seeks to develop a cost-effective and non-invasive screening method for early diagnosis of colorectal cancer. The research focuses on patients who have tested positive in a fecal occult blood test (FOBT) and are referred for colonoscopy. The goal is to improve early detection rates and ultimately reduce mortality associated with colorectal cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a positive FOBT test result from the Colorectal Cancer Early Detection Program and referred for a colonoscopy.

Exclusion Criteria:

* Patients diagnosed with another primary neoplasm in the last 5 years, with the exception of carcinoma in situ of the cervix or non-melanoma skin cancer.
* Patients with severe kidney disease stage IV (creatinine clearance \< 30 ml/min).
* Patients with severe active liver disease (hepatitis, cirrhosis).
* Refusal to sign informed consent.

Where it's running

• Hospital Universitari Sant Joan de Reus
  Reus, Tarragona, Spain Recruiting
• Hospital Universitari Joan XXIII
  Tarragona, Tarragona, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.