Non-invasive forearm optical monitoring to predict fluid response in critically ill patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This proof-of-concept observational study enrolls ICU patients undergoing a passive leg-raising (PLR) maneuver to provoke transient changes in preload. A hybrid diffuse optics (hDOS) probe is placed on the brachioradialis muscle to record microvascular blood flow index (BFI) and tissue oxygen saturation (StO2) while cardiac output (CO) is measured continuously from an arterial-line based pulse waveform monitor. Investigators will examine correlations over time between CO and the microvascular variables and determine whether changes in BFI or StO2 predict a positive CO response (>10% increase). Enrollment and measurements occur at a single center in Sabadell, Spain, for proof-of-concept performance rather than direct clinical decision-making.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Invasive blood pressure monitoring through an arterial line

Exclusion Criteria:

* Patients with suspected pregnancy
* Intra-abdominal hypertension
* Elevated intracranial pressure

Where it's running

• Parc Taulí Hospital Universitari
  Sabadell, Spain/ Barcelona, Spain Recruiting

Study contacts

• Study coordinator: Jaume Mesquida Senior Clinical Researcher, MD
• Email: jmesquida@tauli.cat
• Phone: +34 616722287

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.