Non-invasive evaluation of lung issues in asthma and cystic fibrosis using breath analysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze exhaled breath condensate (EBC) to identify biomarkers associated with pulmonary inflammation and infections in patients with bronchial asthma and cystic fibrosis. By establishing EBC 'breathprints', the researchers hope to correlate these molecular signatures with the severity of lung disease and the presence of specific bacterial infections, particularly from opportunistic pathogens like Pseudomonas aeruginosa. The study will include children and adults with asthma and cystic fibrosis, as well as healthy controls, to validate the effectiveness of EBC as a diagnostic tool. The ultimate goal is to enhance early detection and monitoring of lung conditions in these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children/adults with moderate or IgE mediated asthma
* Children/adults with cystic fibrosis
* Healthy control children/adults without lung disorders

Exclusion Criteria:

\-

Where it's running

• University Hospital Olomouc
  Olomouc, Czechia Recruiting

Study contacts

• Study coordinator: Petr Dzubak, MD, PhD.
• Email: petr.dzubak@upol.cz
• Phone: 585632150

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Acupuncture for Acute Exacerbation of Bronchial Asthma

  This study tests whether adding hand acupuncture to standard asthma treatment helps people with an acute bronchial asthma flare.

  Recruiting Henan University of Traditional Chinese Medicine · Zhengzhou, Henan · NCT07632352

• N95 Masks and Lung Health for Regular Golfers in Wildfire Season

  This study tests whether wearing N95 masks on days with smoky air helps protect lung health for people who golf at least twice a week during wildfire season.

  Recruiting University of Saskatchewan · Saskatoon, SK - Saskatchewan · NCT07620691

• PA9159 inhaler for adults with bronchial asthma

  This test will see if inhaled PA9159 at three dose levels is safe and helps adults with bronchial asthma.

  Recruiting Phase 2 Anhui Palo Alto Pharmaceuticals, Inc. · Nanchang, Jiangxi · NCT07326995

• PA9159 inhaler versus fluticasone for adults with bronchial asthma

  We will test whether the new PA9159 inhaler is safe and works as well as fluticasone for adults with bronchial asthma.

  Recruiting Phase 2 Anhui Palo Alto Pharmaceuticals, Inc. · Nanchang, Jiangxi · NCT07324707

• Improving how adults with COPD and asthma stick to and use their inhalers

  This project will test whether a mobile/web app plus targeted training helps adults with COPD or asthma use their inhalers correctly and keep taking their inhaled medicines.

  Recruiting Charles University, Czech Republic · Hradec Králové · NCT07183657

• Community- or home-based exercise for adults with weakened heart or lungs

  This test will see if an eight-week, community- or home-based exercise program can improve heart and lung function in adults 18–85 with reduced cardiopulmonary fitness.

  Recruiting Guangdong Provincial People's Hospital · Guangzhou, Guangdong · NCT07154355

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.