Non-invasive evaluation for patients with portal hypertension receiving TIPS

Non-invasive Evaluation of Prognostic Parameters for Patients With Transjugular Intrahepatic Portosystemic Shunt (TIPS) Using a Structured Follow up Protocol 2

Observational University Hospital, Bonn · NCT04393519

This study is testing new ways to monitor patients with portal hypertension who are getting a TIPS procedure to see how well they do afterward.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorUniversity Hospital, Bonn Academic / other
Locations1 site (Bonn)
Trial IDNCT04393519 on ClinicalTrials.gov

What this trial studies

This program evaluates non-invasive prognostic parameters in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) due to complications from portal hypertension. Patients will be monitored through a structured follow-up program at the University Hospital Bonn, where clinical and laboratory data will be collected and analyzed for their prognostic value. The study aims to enhance understanding of patient outcomes following TIPS procedures using advanced imaging techniques such as echocardiography, CT scans, and MRIs.

Who should consider this trial

Good fit: Ideal candidates are patients with liver cirrhosis who are eligible for TIPS insertion according to established guidelines.

Not a fit: Patients with contraindications for TIPS will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the management and outcomes of patients with portal hypertension undergoing TIPS.

How similar studies have performed: While there have been studies on TIPS, this specific non-invasive evaluation approach is novel and may provide new insights into patient management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Insertion of TIPS according to guidelines

Exclusion Criteria:

* Contraindication for TIPS

Where this trial is running

Bonn

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Portal Hypertensiontransjugular intrahepatic portosystemic shuntnon-invasive assessmentsTransthoracic echocardiography with Speckle-trackingComputer tomography scanMagnetic resonance imagingCirculating biomarkersElectroencephalography
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.