Clinical trial Recruiting at 1 site Interventional

New treatment approaches for amblyopia using video games and perceptual learning

Official title: Improving Normal and Amblyopic Vision With Video Games and Perceptual Learning

Run by Nova Southeastern University · NCT05522972 · Data updated 2026-11-12

This study is testing whether playing special video games can help improve vision in people with amblyopia, both kids and adults.

Quick facts

Study typeInterventional
SexAll
Enrollment180 (estimated)
SponsorNova Southeastern University
Academic / other
Locations1 site (Fort Lauderdale, Florida)
StatusRecruiting
StartedSeptember 13, 2022
Main results expectedAugust 31, 2029
Study endsAugust 31, 2029
Registry record updatedDecember 16, 2025
Trial IDNCT05522972 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults and children with amblyopia or normal vision who meet specific visual acuity criteria.

Probably not a fit

Patients with ocular pathological conditions or nystagmus may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates innovative treatment methods for amblyopia, a condition that impairs spatial vision. It focuses on understanding neural plasticity in both adults and children by utilizing psychophysical measures. Participants will engage in visual discrimination tasks or play video games specifically designed for amblyopic vision. The study aims to monitor various visual functions throughout the treatment process to assess the effectiveness of these interventions.

Why it matters

Potential benefit: If successful, this approach could significantly improve visual acuity and contrast sensitivity in patients with amblyopia.

How similar studies have gone: Previous studies have indicated that the adult amblyopic brain retains plasticity, suggesting that similar approaches may have been successful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adults and children with normal vision or amblyopia
* amblyopia: interocular VA difference of 0.1 logMAR or more

Exclusion Criteria:

* any ocular pathological conditions, nystagmus

Where it's running

  • Nova Southeastern University College of Optometry
    Fort Lauderdale, Florida, United States
    Recruiting

Study contacts

  • Principal investigator: Roger W Li, OD, PhD — Nova Southeastern University College of Optometry
  • Study coordinator: Roger W Li, OD, PhD
  • Email: wli@nova.edu
  • Phone: 954-262-1436

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.