New treatment approaches for amblyopia using video games and perceptual learning
Official title: Improving Normal and Amblyopic Vision With Video Games and Perceptual Learning
Run by Nova Southeastern University · NCT05522972 · Data updated 2026-11-12
This study is testing whether playing special video games can help improve vision in people with amblyopia, both kids and adults.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 180 (estimated) |
| Sponsor | Nova Southeastern University Academic / other |
| Locations | 1 site (Fort Lauderdale, Florida) |
| Status | Recruiting |
| Started | September 13, 2022 |
| Main results expected | August 31, 2029 |
| Study ends | August 31, 2029 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT05522972 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults and children with amblyopia or normal vision who meet specific visual acuity criteria.
✕Probably not a fit
Patients with ocular pathological conditions or nystagmus may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates innovative treatment methods for amblyopia, a condition that impairs spatial vision. It focuses on understanding neural plasticity in both adults and children by utilizing psychophysical measures. Participants will engage in visual discrimination tasks or play video games specifically designed for amblyopic vision. The study aims to monitor various visual functions throughout the treatment process to assess the effectiveness of these interventions.
Why it matters
Potential benefit: If successful, this approach could significantly improve visual acuity and contrast sensitivity in patients with amblyopia.
How similar studies have gone: Previous studies have indicated that the adult amblyopic brain retains plasticity, suggesting that similar approaches may have been successful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adults and children with normal vision or amblyopia * amblyopia: interocular VA difference of 0.1 logMAR or more Exclusion Criteria: * any ocular pathological conditions, nystagmus
Where it's running
-
Nova Southeastern University College of Optometry
Fort Lauderdale, Florida, United States Recruiting
Study contacts
- Principal investigator: Roger W Li, OD, PhD — Nova Southeastern University College of Optometry
- Study coordinator: Roger W Li, OD, PhD
- Email: wli@nova.edu
- Phone: 954-262-1436
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Psilocybin-assisted therapy to help adults with amblyopia see more clearly
This study tests whether a single or small doses of psilocybin can boost the effectiveness of amblyopia treatment in adults.
-
Augmented Reality Binocular Therapy for Adult Amblyopia
This trial tests a home-based augmented reality binocular therapy to see if it improves vision in adults 18–40 with anisometropic amblyopia, compared with placebo training.
-
Gabor-based visual training for adults with amblyopia
This study tests a computer-based Gabor training program to see if it can improve vision in adults aged 18–39 with amblyopia due to anisometropia or strabismus.
-
Noninvasive brain stimulation plus augmented reality vision therapy for anisometropic amblyopia in adults
This trial tests whether adding HD-tDCS to AR-based dichoptic therapy can improve vision in adults with anisometropic amblyopia.
-
tDCS for paediatric amblyopia
This study tests whether non-invasive brain stimulation (tDCS) can improve vision for children aged 4–14 with amblyopia who didn’t get enough help from patching.
-
Gamified visual training with occlusion for kids with anisometropic amblyopia
This trial tests two kid-friendly digital games plus patching to see if they improve vision and motivation in children aged 4–7 with anisometropic amblyopia compared with patching alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.