Clinical trial Recruiting at 1 site Interventional Ages 16 to 60

New treatment approach for temporomandibular disorders

Official title: Create the New Serial Treatment of Temporomandibular Disorders

Run by Sun Yat-sen University · NCT00932594 · Data updated 2026-11-12

This study is testing a new way to treat jaw pain by adjusting pressure in the jaw joint to see if it helps people with temporomandibular disorders feel better.

More Temporomandibular Disorder trials

Quick facts

Study typeInterventional
Ages16 Years to 60 Years
SexAll
Enrollment4 (estimated)
SponsorSun Yat-sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedJanuary 2006
Main results expectedDecember 2018
Study endsDecember 2026
Registry record updatedMay 20, 2015
Trial IDNCT00932594 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 16-60 with specific symptoms related to TMD, such as limited mouth opening or joint pain.

Probably not a fit

Patients with serious underlying health conditions or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of adjusting temporomandibular joint (TMJ) pressure as a treatment for temporomandibular disorders (TMD). It classifies TMD into three types based on TMJ pressure and provides tailored treatments, including psychogenic therapy, medication, and physical treatments. If initial treatments are ineffective, patients may receive more invasive options like arthrocentesis or arthroscopic treatment. The study will collect clinical data over three years to assess treatment outcomes.

Why it matters

Potential benefit: If successful, this approach could provide a more effective and personalized treatment for patients suffering from temporomandibular disorders.

How similar studies have gone: While there is limited data on this specific approach, similar studies have explored TMJ treatments with varying degrees of success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Limited Month Opening
* Abnormal of the Month Opening Type
* Paint During the Month Open or Close
* Condylar Position Paint
* Clicking of the Temporomandibular Joint
* Enlargement of the Upper Temporomandibular Joint Gap
* Dislocation of the Temporomandibular Disc
* Bone of the Temporomandibular Joint Changement
* Patient in the Age of 16-60
* Voluntary Patient

Exclusion Criteria:

* Dysimmunity Disease
* Dysfunction of Heart Liver and Kidney Disease
* Patient can not do the Guide Line
* Life-threatening Patient
* Serious Limited Mouth Opening
* Epilepsy
* Tetanus
* Pregnancy or Women in the Pregnancy Period
* Supportive Temporomandibular Disease

Where it's running

  • Guanghua School of Stomatology and Hospital of Stomatology
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Botulinum toxin for jaw myofascial pain in adults

    This study tests whether injecting botulinum toxin into jaw muscles helps reduce pain and improve mouth opening in adults with stubborn temporomandibular myofascial pain.

    Recruiting Phase 2 Riphah International University · Islamabad · NCT07847541

  • What predicts how bad TMD is, involving jaw, neck, and posture

    We will test if jaw dysfunction, neck position sense, and head/neck posture relate to how severe temporomandibular disorders are in adults.

    Recruiting Ankara Yildirim Beyazıt University · Ankara · NCT07666360

  • Nerivio in adults and adolescents with chronic TMD headache

    This study tests a Nerivio device to help people 12 and older with chronic temporomandibular disorder and headaches see if the treatment reduces pain.

    Recruiting at 4 sites Theranica · Newark, Delaware and 3 other locations · NCT07639944

  • Daily ear vagus‑nerve stimulation to reduce TMD jaw and facial pain

    This will test whether daily, at‑home gentle electrical stimulation of the ear's vagus nerve can reduce chronic jaw and facial pain in adults with temporomandibular disorder (TMD).

    Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07517172

  • Heat therapy for jaw pain in chronic TMD

    This study tests whether applying local heat to the jaw can reduce pain and jaw fatigue in adults with chronic temporomandibular disorder during a clenching task.

    Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07153107

  • Using Botulinumtoxin A to treat pain in jaw disorders

    This study is testing if Botulinumtoxin A injections can help reduce pain and improve life for people with jaw disorders caused by muscle issues.

    Recruiting Phase 3 Region Stockholm · Stockholm · NCT06941636

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.