New tool to help lung cancer patients understand their illness better
Official title: Information Needs, Preferences, and Understanding Trial (INPUT): A Randomized, Controlled Trial of the Effects of a Screening Tool on Illness Understanding
Run by M.D. Anderson Cancer Center · NCT06743308 · Data updated 2026-11-12
This study tests a new tool to help lung cancer patients better understand their illness and treatment options compared to regular care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | December 16, 2024 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT06743308 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 or over, within three months of a biopsy-confirmed diagnosis of stage IV lung cancer, who are English-speaking and attending follow-up visits at the thoracic medical oncology clinic.
✕Probably not a fit
Patients with cognitive impairment or dementia requiring a surrogate decision maker may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates a novel screening tool designed to assess the information needs, preferences, and understanding of patients with metastatic or incurable lung cancer. The study compares the effectiveness of this tool against usual care in improving patients' comprehension of their illness and prognosis. By facilitating more frequent discussions about disease status and treatment goals, the trial aims to align medical care with patients' values and preferences. Participants will be monitored over a three-month period to measure changes in their perception of curability.
Why it matters
Potential benefit: If successful, this tool could significantly enhance patients' understanding of their illness, leading to more informed decision-making regarding their care.
How similar studies have gone: While similar approaches have been explored, this specific tool and its application in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Within 3 months of biopsy-confirmed diagnosis of stage IV lung cancer * Age 18 or over * English speaking * Attending a follow-up visit at the thoracic medical oncology clinic * Plans to receive or actively undergoing cancer-directed systemic treatment at MD Anderson Exclusion Criteria: • Diagnosis of cognitive impairment or dementia requiring a surrogate decision maker
Where it's running
-
MD Anderson Cancer Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Kayley Ancy, MD — M.D. Anderson Cancer Center
- Study coordinator: Kayley M Ancy, MD
- Email: kmclemings@mdanderson.org
- Phone: 832-729-1621
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.