New tool to help lung cancer patients understand their illness better

Information Needs, Preferences, and Understanding Trial (INPUT): A Randomized, Controlled Trial of the Effects of a Screening Tool on Illness Understanding

Not applicable Interventional M.D. Anderson Cancer Center · NCT06743308

This study tests a new tool to help lung cancer patients better understand their illness and treatment options compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorM.D. Anderson Cancer Center Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06743308 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates a novel screening tool designed to assess the information needs, preferences, and understanding of patients with metastatic or incurable lung cancer. The study compares the effectiveness of this tool against usual care in improving patients' comprehension of their illness and prognosis. By facilitating more frequent discussions about disease status and treatment goals, the trial aims to align medical care with patients' values and preferences. Participants will be monitored over a three-month period to measure changes in their perception of curability.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 or over, within three months of a biopsy-confirmed diagnosis of stage IV lung cancer, who are English-speaking and attending follow-up visits at the thoracic medical oncology clinic.

Not a fit: Patients with cognitive impairment or dementia requiring a surrogate decision maker may not benefit from this study.

Why it matters

Potential benefit: If successful, this tool could significantly enhance patients' understanding of their illness, leading to more informed decision-making regarding their care.

How similar studies have performed: While similar approaches have been explored, this specific tool and its application in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Within 3 months of biopsy-confirmed diagnosis of stage IV lung cancer
* Age 18 or over
* English speaking
* Attending a follow-up visit at the thoracic medical oncology clinic
* Plans to receive or actively undergoing cancer-directed systemic treatment at MD Anderson

Exclusion Criteria:

• Diagnosis of cognitive impairment or dementia requiring a surrogate decision maker

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung CarcinomaMetastatic Lung CarcinomaStage IV Lung Cancer AJCC v8
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.