Clinical trial Recruiting at 1 site Interventional Ages 6 and up

New test for diagnosing amoxicillin allergy

Official title: Diagnosing Drug Allergy the T is the Key

Run by University Hospital, Antwerp · NCT06409884 · Data updated 2026-11-12

This study is testing a new blood test to see if it can accurately diagnose amoxicillin allergies in people who may have them.

Quick facts

Study typeInterventional
Ages6 Years and up
SexAll
Enrollment300 (estimated)
SponsorUniversity Hospital, Antwerp
Academic / other
Locations1 site (Edegem, Antwerp)
StatusRecruiting
StartedMay 21, 2024
Main results expectedSeptember 30, 2027
Study endsSeptember 30, 2027
Registry record updatedMay 14, 2026
Trial IDNCT06409884 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 6 years and older with a suspected history of amoxicillin allergy.

Probably not a fit

Patients who are pregnant, breastfeeding, or unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to validate a novel T-cell activation test for diagnosing amoxicillin allergy. Participants will undergo blood collection and, when applicable, allergy skin testing during multiple hospital visits. The study focuses on improving the reliability and applicability of allergy diagnostics, addressing the challenges of current testing methods. By utilizing flow-based intracellular trapping and staining techniques, the researchers hope to create a safe and effective diagnostic tool that could streamline the identification of drug allergies.

Why it matters

Potential benefit: If successful, this test could provide a more accurate and safer method for diagnosing amoxicillin allergies, reducing unnecessary challenges and misdiagnoses.

How similar studies have gone: Other studies have explored T-cell activation tests for drug allergies, but this specific approach is novel and aims to enhance diagnostic accuracy.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Participants are eligible if they:

* Are ≥ 6 years
* Are capable of informed consent, or if appropriate, participants have an acceptable individual capable of giving consent on the participant's behalf (e.g. parent or guardian of a child under 18 years of age)
* Have a suspected history of amoxicillin allergy

Exclusion Criteria:

* Patients who are lacking capacity or do not have an acceptable individual capable to provide informed consent
* Pregnant women
* Breastfeeding women

Where it's running

  • Antwerp University Hospital
    Edegem, Antwerp, Belgium
    Recruiting

Study contacts

  • Principal investigator: Didier Ebo, PhD — University Hospital, Antwerp
  • Study coordinator: Didier Ebo, PhD
  • Email: Didier.Ebo@uza.be
  • Phone: +3238215027

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.