New techniques for treating chronic lumbar radicular pain
Effectiveness of Transgrade vs Interlaminar Epidural Steroid Injection for Chronic Unilateral Lumbar Radicular Pain
NA · Ain Shams University · NCT06092749
This study is testing two new ways to give pain relief for people who have long-lasting pain in one leg and back pain that hasn't gotten better with regular treatments.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Ain Shams University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06092749 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates two innovative techniques for managing chronic unilateral lumbar radicular pain: the Transgrade (TG) epidural injection and the Interlaminar (IL) epidural steroid injection. The TG technique utilizes a Racz-Coudé needle to access the epidural space at a unique angle, while the IL technique delivers medication through a needle inserted between adjacent vertebrae. Both methods aim to provide relief for patients who have not responded adequately to conventional treatments. The study focuses on patients with a history of persistent pain in one leg accompanied by back pain.
Who should consider this trial
Good fit: Ideal candidates are individuals with a history of persistent unilateral leg pain and back pain for over six months who have not found relief from standard treatments.
Not a fit: Patients who have undergone previous lumbar spinal surgery or have certain medical conditions such as myelopathy or psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer new, effective treatment options for patients suffering from chronic neuropathic lumbar pain.
How similar studies have performed: While the specific techniques being tested may be novel, similar approaches in managing chronic pain have shown varying degrees of success in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 6-month history of persistent pain in one leg with back pain. * Capable of giving informed consent. * Unsatisfactory response to conventional treatments including physical therapy or medications with a numeric rating scale (NRS) ≥ 5. Exclusion Criteria: * Previous lumbar spinal surgery. * Myelopathy. * Rheumatoid disorders. * Psychiatric disorders * Bleeding or coagulation disorders
Where this trial is running
Cairo
- Ain-Shams University Hospitals — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Ibrahim Mamdouh Esmat
- Email: ibrahim_mamdouh@med.asu.edu.eg
- Phone: 01001241928
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Neuropathic Pain