New exercise program for hospitalized cystic fibrosis patients

Feasibility of a New Model for Exercise Prescription Combined with Behavior Modification in Cystic Fibrosis

Not applicable Interventional University of Alabama at Birmingham · NCT04075864

This study is testing a new exercise program for hospitalized cystic fibrosis patients to see if it helps them get stronger and stay active after they leave the hospital.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment12 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Alabama at Birmingham Academic / other
Locations1 site (Birmingham, Alabama)
Trial IDNCT04075864 on ClinicalTrials.gov

What this trial studies

This study aims to implement a structured exercise program combined with behavioral counseling for patients hospitalized due to cystic fibrosis exacerbations. Participants will engage in supervised exercise six days a week, incorporating both aerobic and resistance training tailored to their abilities. The program is designed to promote long-term adherence to physical activity by initiating exercise during a period of heightened awareness of their health decline. The approach includes monitoring heart rate and perceived exertion to ensure safety and effectiveness.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a confirmed diagnosis of cystic fibrosis who are currently experiencing a pulmonary exacerbation and are hospitalized.

Not a fit: Patients who are currently exercising more than 60 minutes per week or have recent severe pulmonary complications may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could improve lung function and overall health outcomes for cystic fibrosis patients.

How similar studies have performed: While this approach is innovative, similar studies have shown that structured exercise can be beneficial for patients with chronic respiratory conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Confirmed diagnosis of CF
2. 18 years old or older
3. Current pulmonary exacerbation with planned UAB hospitalization for at least 10 days
4. Willing to participate in a regular, ongoing exercise program
5. Access to broadband internet

Exclusion Criteria:

1. Currently exercising more than 60 min/week
2. Massive hemoptysis or pneumothorax in past 3 months
3. Neuromusculoskeletal impairments that preclude exercise

Where this trial is running

Birmingham, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cystic Fibrosis
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.