New diagnostic strategy for traumatic brain injury biomarkers
The Research for New Clinical Diagnostic Strategy of Specific Biomarkers for Traumatic Brain Injury
This study is testing a new way to find specific markers in the blood that can help doctors better diagnose and predict outcomes for people with traumatic brain injuries.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 450 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Beijing Tiantan Hospital Academic / other |
| Locations | 1 site (Hefei, Anhui) |
| Trial ID | NCT03976492 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop a new clinical diagnostic strategy for identifying specific biomarkers associated with traumatic brain injury (TBI). It focuses on improving the assessment of early neurological function and prognosis in TBI patients, addressing limitations of current methods like the Glasgow Coma Score and CT scans. By identifying biomarkers, the study seeks to enhance the accuracy of diagnosing brain injuries and predicting potential long-term disabilities. The research will involve patients with brain injuries within 24 hours of occurrence and a control group with non-brain injuries.
Who should consider this trial
Good fit: Ideal candidates include males and females aged 18 to 65 who have sustained a brain injury within 24 hours.
Not a fit: Patients under 18, those with a history of central nervous system disorders, or severe metabolic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of traumatic brain injuries, improving patient outcomes.
How similar studies have performed: While there have been studies exploring biomarkers in TBI, this specific approach to developing a new diagnostic strategy is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male and Female, aged from 18 to 65. 2. Patients with brain injury within 24 hours after injury 3. Non-brain injury group refers to patients with limb injury or systemic injury except brain injury. 4. The subject reads and fully understands the instructions of the patients and signs the informed consent. Exclusion Criteria: 1. Male or female, aged below 18. 2. Patients with definite history of central nervous system or cardiovascular system or taking drugs affecting the central nervous system. 3. Patients with severe metabolic diseases. 4. Pregnancy.
Where this trial is running
Hefei, Anhui
- The First Affiliated Hospital of Anhui Medical University — Hefei, Anhui, China (Recruiting)
Study contacts
- Study coordinator: Fei Niu
- Email: nf520621@163.com
- Phone: +86-18701075929
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.