Neuroprolotherapy for menstrual pain relief
The Treatment Efficacy of Posterior Tibia Nerve Neuroprolotherapy on Dysmenorrhea
This study is testing if a new treatment called neuroprolotherapy can help women with menstrual pain feel better compared to taking acetaminophen.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Taichung Armed Forces General Hospital Government |
| Locations | 1 site (Taichung, Other (Non US)) |
| Trial ID | NCT06294743 on ClinicalTrials.gov |
What this trial studies
This crossover study evaluates the effectiveness of posterior tibial nerve neuroprolotherapy in alleviating dysmenorrhea. Sixty women aged 20-50 with normal menstrual cycles and menstrual pain will be randomly assigned to two groups. One group will receive neuroprolotherapy for the first two menstrual cycles followed by acetaminophen, while the other group will receive acetaminophen first and then neuroprolotherapy. The primary outcome is the improvement in pain measured by the Visual Analog Scale, with secondary outcomes including quality of life assessments.
Who should consider this trial
Good fit: Ideal candidates are women aged 18-50 who experience normal menstrual cycles with associated menstrual pain.
Not a fit: Patients with malignant tumors, pregnancy, or those on hormonal contraceptives may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a new, effective option for women suffering from dysmenorrhea.
How similar studies have performed: While neuroprolotherapy is a relatively novel approach for this condition, similar studies have shown promise in pain management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * women aged 18-50 who experience normal menstrual cycles accompanied by menstrual pain Exclusion Criteria: * Malignant tumors requiring treatment. * Pregnant * Those who have other acute and chronic pain and are receiving relevant drug treatment. * Those who are allergic to acetaminophen or have contraindications. * Those who use hormonal contraceptives at the same time. * Those with coagulation disorders or taking anticoagulant drugs.
Where this trial is running
Taichung, Other (Non US)
- Taichung Armed Forces General Hospital — Taichung, Other (Non US), Taiwan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.