Neurophysiological changes from balance training in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of perturbation-based training (PBT) on postural balance and neurophysiological changes in older adults. A total of 88 participants aged 60 and above will be randomly assigned to either the PBT group or an active control group. Both groups will engage in treadmill walking, but only the PBT group will experience induced perturbations during their sessions. The study aims to assess changes in postural stability and brain connectivity through behavioral assessments and MRI scans before and after the training, with follow-up evaluations for fall incidents over the next year.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged ≥ 60 years old
* Community-dwelling
* Right-handed
* Able to communicate effectively in Cantonese or Mandarin
* Able to walk independently on level ground for ≥ 30 minutes
* Abbreviated Mental Test (Hong Kong version) score ≥ 6

Exclusion Criteria:

* Metal implants (e.g. pacemaker, artificial cochlea)
* Uncorrected vision or hearing impairment
* Osteoporosis
* Hip or knee replacement within the last year
* Musculoskeletal, cardiovascular, mental, or neurological disorders (such as Parkinson's disease) which can affect MRI examination, balance control, or exercise participation.

Where it's running

• The Hong Kong Polytechnic University
  Hong Kong, Hong Kong Recruiting

Study contacts

• Principal investigator: Sau Lan Tsang, PhD — The Hong Kong Polytechnic University
• Study coordinator: Sau Lan Tsang, PhD
• Email: charlotte-sl.tsang@polyu.edu.hk
• Phone: 852 3400 8965

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.