Neurofeedback with implanted brain electrodes for neurological disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of neurofeedback through implanted deep brain stimulation (DBS) electrodes to treat conditions such as Parkinson's disease, epilepsy, and essential tremor. By analyzing local field potentials (LFP) from the subthalamic nucleus, researchers aim to understand and potentially modulate abnormal neuronal activity associated with these disorders. Patients undergoing the implantation of a Percept™ PC neurostimulator will be monitored for their responses to neurofeedback, providing insights into the correlation between brain activity and motor symptoms. The study seeks to enhance the therapeutic effects of DBS by leveraging real-time feedback from the brain's electrical activity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

patients undergoing clinically indicated implantation of a Percept™ PC neurostimulator, age ≥ 18 years as well as planned hospitalisation of ≥ 3 days after operation

Exclusion Criteria:

minimal prognosticated survival of less than 1 year, reduced state of consciousness (i. e. Glasgow Coma Scale \< 15), inability to communicate (in terms of hearing, seeing, speaking and understanding), other significant concomitant diseases (e. g. cardiovascular disease, infectious disease, isolation), inability to follow procedures, insufficient knowledge of project language, inability to give consent and unlikeliness to follow protocol.

Where it's running

• ETH Zurich
  Zurich, Canton of Zurich, Switzerland Recruiting

Study contacts

• Principal investigator: Oliver Bichsel, MD, MSc ETH — ETH Zurich
• Study coordinator: Oliver Bichsel, MD, MSc ETH
• Email: oliver.bichsel@hest.ethz.ch
• Phone: +41 44 510 72 34

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.