Neural mobilization to reduce pain, improve balance, and boost quality of life in diabetic neuropathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-blinded randomized controlled trial will enroll 32 people with type 2 diabetes and diabetic peripheral neuropathy and randomize them to receive either neural mobilization plus balance training with standard care or balance training with standard care alone. Interventions will be delivered twice weekly for six weeks in 30-minute sessions at a single center. Outcomes measured before and after the intervention include pain (Numeric Pain Rating Scale), postural balance (Berg Balance Scale), and disease-specific quality of life (Norfolk QOL-DN). Participants will be screened with the Michigan Neuropathy Screening Instrument and must meet age and symptom criteria to enroll.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both genders.
* Diagnosed cases of Diabetic Peripheral Neuropathy
* Age 50-75 years.
* Patients having history of type 2 Diabetes for at least 5 years.
* Presence of neuropathic symptoms (pain, numbness, tingling, balance issues).
* Patient having mild to moderate pain according to NPRS

Exclusion Criteria:

* Patients with Neurological Disorders like Stroke, multiple sclerosis, Parkinson's disease.
* Chronic Pain Conditions or Conditions unrelated to DPN (e.g., fibromyalgia, osteoarthritis).
* Foot Ulcers/Infection: Active ulcers or infections on lower limbs.
* Uncontrolled Diabetes
* Severe Balance Impairment Individuals unable to perform basic balance tests (e.g., unable to stand unaided for a few seconds).

Where it's running

• Foundation University College of Physical Therapy
  Islamabad, Pakistan Recruiting

Study contacts

• Study coordinator: Maria Ghulam Fareed, DPT
• Email: mariafareed@000gmail.com
• Phone: +92 3458353129

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Reactive Balance Training vs Task-Oriented Training for Postural Stability in Diabetic Neuropathy

  This trial tests whether Reactive Balance Training or Task-Oriented Training improves postural stability in adults with diabetic peripheral neuropathy.

  Recruiting Foundation University Islamabad · Islamabad · NCT07827417

• Horse Riding Simulator Added to Core Exercises in Adolescents with Idiopathic Scoliosis

  In adolescents with idiopathic scoliosis, adding a horse riding simulator to a core stabilization program is being tested to see if it improves breathing muscle strength, balance, quality of life, and how they feel about their posture.

  Recruiting Bezmialem Vakif University · Istanbul · NCT07758712

• Diaphragmatic Breathing Training in Combat Sport Athletes with Dysfunctional Breathing

  This study tests whether diaphragmatic breathing training can improve breathing patterns, core stability, and sport-related performance in combat sport athletes with dysfunctional breathing.

  Recruiting National Cheng Kung University · Tainan · NCT07717801

• Extended-release Pregabalin for nerve pain from diabetes or shingles

  This phase 3 study tests an extended-release form of pregabalin to see if it reduces nerve-pain symptoms in adults with diabetic neuropathy or postherpetic neuralgia.

  Recruiting at 15 sites Phase 3 Brainfarma Industria Química e Farmacêutica S/A · Salvador, Estado de Bahia and 14 other locations · NCT07712913

• Balance and gait in multiple sclerosis: linking motion data to function

  Researchers will see if precise motion measurements of balance and walking relate to everyday functional tests in adults with MS.

  Recruiting at 2 sites University of Patras · Ioannina and 1 other locations · NCT07630311

• Reactive balance training vs. conventional balance training for tennis players

  In competitive tennis players, this study tests whether reactive balance training improves dynamic stability and change-of-direction performance more than traditional balance training over six weeks.

  Recruiting Ibadat International University, Islamabad · Islamabad · NCT07590674

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.