Neoadjuvant chemotherapy for pancreatic cancer using different drug combinations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of two different neoadjuvant chemotherapy regimens for patients with pancreatic adenocarcinoma. Participants will receive either gemcitabine plus S-1 or gemcitabine plus nab-paclitaxel before undergoing elective pancreatectomy. The goal is to determine which chemotherapy combination yields better outcomes in terms of tumor response and surgical results. The study is designed as a Phase 2 and Phase 3 interventional trial to assess the comparative efficacy of these treatment approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

elective pancreatectomy for pancreatic cancer

Exclusion Criteria:

a previous cancer surgery a body weight loss of \>10% during the 6 months before surgery the presence of distant metastases seriously impaired function of vital organs because of respiratory, renal, or heart disease.

Where it's running

• Takehiro Okabayashi
  Kochi, Japan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.