Nationwide evaluation of acute kidney injury in hospitalized patients in China

China Collaborative Study on Epidemiology of Acute Kidney Injury

Observational Guangdong Provincial People's Hospital · NCT03054142

This study looks at how common acute kidney injury is in hospitalized patients in China and what factors might increase the risk of developing it.

Quick facts

Study typeObservational
Enrollment1000000 (estimated)
SexAll
SponsorGuangdong Provincial People's Hospital Academic / other
Locations1 site (Guangzhou, Guangdong)
Trial IDNCT03054142 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the burden of acute kidney injury (AKI) among hospitalized patients in China from 2011 to 2016. By analyzing changes in serum creatinine levels based on the 2012 Kidney Disease Improving Global Outcomes (KDIGO) criteria, the study seeks to identify the prevalence and risk factors associated with AKI. The data will be collected from a nationwide cohort of patients, providing valuable insights into the epidemiology of this condition in the Chinese healthcare context.

Who should consider this trial

Good fit: Ideal candidates for this study are hospitalized patients diagnosed with acute kidney injury based on serum creatinine changes.

Not a fit: Patients with end-stage kidney disease or those who have undergone nephrectomy or kidney transplantation will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of acute kidney injury, leading to improved prevention and management strategies for patients.

How similar studies have performed: While similar studies have been conducted globally, this specific nationwide evaluation in China is novel and aims to fill a significant gap in local epidemiological data.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patients diagnosed on the basis of changes in serum creatinine according to the criteria of 2012 Kidney Disease Improving Global Outcomes(KDIGO)

Exclusion Criteria:

* Serum creatinine record less than two times during hospitalization
* Patients being diagnosed with End-stage kidney disease (chronic kidney disease stage 5)
* Nephrectomy
* Kidney transplantation
* Peak serum creatinine of less than 53µ mol/L
* Serum creatinine decrease after amputation

Where this trial is running

Guangzhou, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Kidney Injury
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.