Clinical trial Recruiting at 1 site Observational Ages 1 Day to 18

National survey on bacterial meningitis in children

Official title: National Observatory of Bacterial Meningitis in Children and Newborns

Run by Association Clinique Thérapeutique Infantile du val de Marne · NCT04664569 · Data updated 2026-11-12

This study is trying to learn more about bacterial meningitis in children by looking at which bacteria are causing it and how things have changed since the introduction of vaccines.

Quick facts

Study typeObservational
Ages1 Day to 18 Years
SexAll
Enrollment10000 (estimated)
SponsorAssociation Clinique Thérapeutique Infantile du val de Marne
Academic / other
Locations1 site (Créteil)
StatusRecruiting
StartedJanuary 1, 2001
Main results expectedJanuary 1, 2030
Study endsJanuary 1, 2030
Registry record updatedApril 28, 2026
Trial IDNCT04664569 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are children exhibiting clinical signs of meningitis with confirmed positive laboratory tests.

Probably not a fit

Patients without clinical signs of meningitis or those who do not meet the laboratory confirmation criteria may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the epidemiology of bacterial meningitis in children, focusing on the bacteria responsible for the condition. It will collect data from clinical cases that show signs of meningitis and have positive results from cerebrospinal fluid cultures or tests. The study will help understand how the epidemiology of bacterial meningitis has evolved, particularly in light of the use of various conjugate vaccines. By gathering this information, the study seeks to inform better treatment recommendations and public health strategies.

Why it matters

Potential benefit: If successful, this study could enhance understanding of bacterial meningitis in children, leading to improved treatment and prevention strategies.

How similar studies have gone: Other studies have shown success in understanding bacterial meningitis epidemiology, but this specific national survey approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and/or positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and/or positive CSF polymerase chain reaction (PCR), and/or positive blood culture with CSF pleocytosis (\> 10 cells/µL).
* purpura fulminans

Exclusion Criteria:

\-

Where it's running

  • Activ
    Créteil, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.