National survey on bacterial meningitis in children
Official title: National Observatory of Bacterial Meningitis in Children and Newborns
Run by Association Clinique Thérapeutique Infantile du val de Marne · NCT04664569 · Data updated 2026-11-12
This study is trying to learn more about bacterial meningitis in children by looking at which bacteria are causing it and how things have changed since the introduction of vaccines.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Day to 18 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Association Clinique Thérapeutique Infantile du val de Marne Academic / other |
| Locations | 1 site (Créteil) |
| Status | Recruiting |
| Started | January 1, 2001 |
| Main results expected | January 1, 2030 |
| Study ends | January 1, 2030 |
| Registry record updated | April 28, 2026 |
| Trial ID | NCT04664569 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children exhibiting clinical signs of meningitis with confirmed positive laboratory tests.
✕Probably not a fit
Patients without clinical signs of meningitis or those who do not meet the laboratory confirmation criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the epidemiology of bacterial meningitis in children, focusing on the bacteria responsible for the condition. It will collect data from clinical cases that show signs of meningitis and have positive results from cerebrospinal fluid cultures or tests. The study will help understand how the epidemiology of bacterial meningitis has evolved, particularly in light of the use of various conjugate vaccines. By gathering this information, the study seeks to inform better treatment recommendations and public health strategies.
Why it matters
Potential benefit: If successful, this study could enhance understanding of bacterial meningitis in children, leading to improved treatment and prevention strategies.
How similar studies have gone: Other studies have shown success in understanding bacterial meningitis epidemiology, but this specific national survey approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and/or positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and/or positive CSF polymerase chain reaction (PCR), and/or positive blood culture with CSF pleocytosis (\> 10 cells/µL). * purpura fulminans Exclusion Criteria: \-
Where it's running
-
Activ
Créteil, France Recruiting
Study contacts
- Principal investigator: Robert Cohen — Association Clinique Thérapeutique Infantile du val de Marne
- Study coordinator: Corinne Levy, MD
- Email: corinne.levy@activ-france.fr
- Phone: 0033148850404
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.