National survey on bacterial meningitis in children
National Observatory of Bacterial Meningitis in Children and Newborns
This study is trying to learn more about bacterial meningitis in children by looking at which bacteria are causing it and how things have changed since the introduction of vaccines.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 1 Day to 18 Years |
| Sex | All |
| Sponsor | Association Clinique Thérapeutique Infantile du val de Marne Academic / other |
| Locations | 1 site (Créteil) |
| Trial ID | NCT04664569 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the epidemiology of bacterial meningitis in children, focusing on the bacteria responsible for the condition. It will collect data from clinical cases that show signs of meningitis and have positive results from cerebrospinal fluid cultures or tests. The study will help understand how the epidemiology of bacterial meningitis has evolved, particularly in light of the use of various conjugate vaccines. By gathering this information, the study seeks to inform better treatment recommendations and public health strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are children exhibiting clinical signs of meningitis with confirmed positive laboratory tests.
Not a fit: Patients without clinical signs of meningitis or those who do not meet the laboratory confirmation criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of bacterial meningitis in children, leading to improved treatment and prevention strategies.
How similar studies have performed: Other studies have shown success in understanding bacterial meningitis epidemiology, but this specific national survey approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and/or positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and/or positive CSF polymerase chain reaction (PCR), and/or positive blood culture with CSF pleocytosis (\> 10 cells/µL). * purpura fulminans Exclusion Criteria: \-
Where this trial is running
Créteil
- Activ — Créteil, France (Recruiting)
Study contacts
- Principal investigator: Robert Cohen — Association Clinique Thérapeutique Infantile du val de Marne
- Study coordinator: Corinne Levy, MD
- Email: corinne.levy@activ-france.fr
- Phone: 0033148850404
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.