Clinical trial Recruiting at 1 site Observational Ages 18 and up

National database for infective endocarditis in France

Official title: French National Observatory on Infective Endocarditis

Run by Central Hospital, Nancy, France · NCT03272724 · Data updated 2026-11-12

This study is creating a national database to collect and analyze information about patients with infective endocarditis in France to better understand their treatment and outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorCentral Hospital, Nancy, France
Academic / other
Locations1 site (Vandœuvre-lès-Nancy)
StatusRecruiting
StartedJanuary 1, 1991
Main results expectedDecember 31, 2026
Study endsDecember 31, 2027
Registry record updatedSeptember 23, 2025
Trial IDNCT03272724 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include major patients diagnosed with definite or possible infective endocarditis who are being treated at participating centers.

Probably not a fit

Patients who refuse to participate or do not meet the diagnostic criteria for endocarditis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observatory aims to create a comprehensive national database for infective endocarditis by collecting standardized data from various volunteer centers across France. It will gather clinical, biological, microbiological, and therapeutic information about patients diagnosed with infective endocarditis during their hospitalization. The study will analyze risk factors, prognosis, management practices, and treatment strategies, including antibiotic and surgical interventions. Data will be recorded using electronic case report forms to ensure consistency and accuracy.

Why it matters

Potential benefit: If successful, this observatory could enhance understanding of infective endocarditis and improve patient management and treatment outcomes.

How similar studies have gone: While similar observational studies have been conducted, this specific national observatory approach is relatively novel in its comprehensive data collection and analysis.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Major Patient
* Supported in one of the participating centers
* The application of diagnostic classification criteria of Duke modified by Li is carried out after collection of all the data at the end of the patient's hospitalization. Only patients meeting criteria for definite or possible endocarditis will be included in the analyses.
* Registered with the French social security system

Exclusion Criteria:

• Refusal of the patient to participate.

Where it's running

  • Chru
    Vandœuvre-lès-Nancy, France
    Recruiting

Study contacts

  • Principal investigator: Christine SELTON-SUTY, MD — CHRU Nancy
  • Study coordinator: Nadine JUGE, PhD
  • Email: n.juge@chru-nancy.fr

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.