National database for infective endocarditis in France
Official title: French National Observatory on Infective Endocarditis
Run by Central Hospital, Nancy, France · NCT03272724 · Data updated 2026-11-12
This study is creating a national database to collect and analyze information about patients with infective endocarditis in France to better understand their treatment and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Vandœuvre-lès-Nancy) |
| Status | Recruiting |
| Started | January 1, 1991 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | September 23, 2025 |
| Trial ID | NCT03272724 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include major patients diagnosed with definite or possible infective endocarditis who are being treated at participating centers.
✕Probably not a fit
Patients who refuse to participate or do not meet the diagnostic criteria for endocarditis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observatory aims to create a comprehensive national database for infective endocarditis by collecting standardized data from various volunteer centers across France. It will gather clinical, biological, microbiological, and therapeutic information about patients diagnosed with infective endocarditis during their hospitalization. The study will analyze risk factors, prognosis, management practices, and treatment strategies, including antibiotic and surgical interventions. Data will be recorded using electronic case report forms to ensure consistency and accuracy.
Why it matters
Potential benefit: If successful, this observatory could enhance understanding of infective endocarditis and improve patient management and treatment outcomes.
How similar studies have gone: While similar observational studies have been conducted, this specific national observatory approach is relatively novel in its comprehensive data collection and analysis.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Major Patient * Supported in one of the participating centers * The application of diagnostic classification criteria of Duke modified by Li is carried out after collection of all the data at the end of the patient's hospitalization. Only patients meeting criteria for definite or possible endocarditis will be included in the analyses. * Registered with the French social security system Exclusion Criteria: • Refusal of the patient to participate.
Where it's running
-
Chru
Vandœuvre-lès-Nancy, France Recruiting
Study contacts
- Principal investigator: Christine SELTON-SUTY, MD — CHRU Nancy
- Study coordinator: Nadine JUGE, PhD
- Email: n.juge@chru-nancy.fr
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Etiologic Diagnosis Algorithm in Infective Endocarditis
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This study tests whether a rifampin-free antibiotic regimen can be as effective as a rifampin-containing regimen for adults with staphylococcal prosthetic valve endocarditis.
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Improving health and quality of life for patients recovering from infective endocarditis through cardiac rehabilitation
This study is testing if joining a cardiac rehabilitation program can help people recovering from infective endocarditis feel healthier and improve their quality of life.
-
Echocardiography versus no echocardiography for Staphylococcus aureus bloodstream infection with VIRSTA score <3
This trial tests whether it is safe to skip routine echocardiography in adults hospitalized with Staphylococcus aureus bloodstream infection who have a VIRSTA score under 3.
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Barts Endocarditis Registry
This registry collects health, imaging, microbiology, treatment, and outcome information from adults with infective endocarditis seen at Barts Heart Centre to learn which approaches work best.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.