National database for infective endocarditis in France

French National Observatory on Infective Endocarditis

Observational Central Hospital, Nancy, France · NCT03272724

This study is creating a national database to collect and analyze information about patients with infective endocarditis in France to better understand their treatment and outcomes.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorCentral Hospital, Nancy, France Academic / other
Locations1 site (Vandœuvre-lès-Nancy)
Trial IDNCT03272724 on ClinicalTrials.gov

What this trial studies

This observatory aims to create a comprehensive national database for infective endocarditis by collecting standardized data from various volunteer centers across France. It will gather clinical, biological, microbiological, and therapeutic information about patients diagnosed with infective endocarditis during their hospitalization. The study will analyze risk factors, prognosis, management practices, and treatment strategies, including antibiotic and surgical interventions. Data will be recorded using electronic case report forms to ensure consistency and accuracy.

Who should consider this trial

Good fit: Ideal candidates include major patients diagnosed with definite or possible infective endocarditis who are being treated at participating centers.

Not a fit: Patients who refuse to participate or do not meet the diagnostic criteria for endocarditis will not benefit from this study.

Why it matters

Potential benefit: If successful, this observatory could enhance understanding of infective endocarditis and improve patient management and treatment outcomes.

How similar studies have performed: While similar observational studies have been conducted, this specific national observatory approach is relatively novel in its comprehensive data collection and analysis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Major Patient
* Supported in one of the participating centers
* The application of diagnostic classification criteria of Duke modified by Li is carried out after collection of all the data at the end of the patient's hospitalization. Only patients meeting criteria for definite or possible endocarditis will be included in the analyses.
* Registered with the French social security system

Exclusion Criteria:

• Refusal of the patient to participate.

Where this trial is running

Vandœuvre-lès-Nancy

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Infective Endocarditis
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.