National cohort of children with respiratory issues in Switzerland
Swiss Paediatric Airway Cohort
This study looks at children in Switzerland with breathing problems to see how these issues affect their health and treatment over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6000 (estimated) |
| Ages | 0 Years to 16 Years |
| Sex | All |
| Sponsor | University of Bern Academic / other |
| Locations | 12 sites (Vienna and 11 other locations) |
| Trial ID | NCT03505216 on ClinicalTrials.gov |
What this trial studies
The Swiss Paediatric Airway Cohort (SPAC) is a prospective observational cohort that collects data from children and adolescents in Switzerland who experience recurrent wheeze, cough, and exercise- or sleep-related respiratory problems. It aims to investigate clinical phenotypes, prognosis, diagnosis, and treatment of these conditions through comprehensive baseline assessments and ongoing follow-up via questionnaires. The study includes 4344 patients from 10 clinics across Switzerland, utilizing real-life data to enhance understanding of respiratory issues in pediatric populations. Participation involves routine clinical care without additional tests specifically for the study.
Who should consider this trial
Good fit: Ideal candidates are children and adolescents aged 0-16 years who are residents of Switzerland and have been referred to a pediatric outpatient clinic for respiratory symptoms.
Not a fit: Patients with prior diagnoses of cystic fibrosis, primary ciliary dyskinesia, severe heart disease, oncological disease, neuromuscular disease, or severe disability may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the management and treatment of common respiratory problems in children.
How similar studies have performed: Other studies have successfully utilized cohort approaches to investigate pediatric respiratory conditions, making this a well-supported methodology.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children and adolescents aged 0-16 years * Resident in Switzerland * Seen in a paediatric pulmonary outpatient clinic due to respiratory problems * Parents and patients above age 14 must be able to sign an informed consent form Exclusion Criteria: Prior diagnosis of cystic fibrosis, primary ciliary dyskinesia, severe heart disease, oncological disease, neuromuscular disease or severe disability
Where this trial is running
Vienna and 11 other locations
- Vienna Open Medical Institute — Vienna, Austria (Completed)
- Children's hospital Aarau — Aarau, Switzerland (Active_not_recruiting)
- University Children's hospital Basel, UKBB — Basel, Switzerland (Recruiting)
- Institute of Social and Preventive Medicine — Bern, Switzerland (Recruiting)
- University Children's Hospital Bern, Inselspital — Bern, Switzerland (Recruiting)
- Children's Hospital Chur — Chur, Switzerland (Recruiting)
- Pulmonology clinic, Horgen — Horgen, Switzerland (Recruiting)
- University Children's hospital Lausane, CHUV — Lausanne, Switzerland (Recruiting)
- Children's hospital Lucerne — Lucerne, Switzerland (Recruiting)
- Children's hospital St. Gallen — Sankt Gallen, Switzerland (Active_not_recruiting)
- Pulmonology clinic, Worb — Worb, Switzerland (Recruiting)
- University Children's Hospital Zurich — Zurich, Switzerland (Recruiting)
Study contacts
- Study coordinator: Claudia E Kuehni, Prof.
- Email: claudia.kuehni@unibe.ch
- Phone: +41(0)316843507
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.