National blood pressure screening for children in South Africa

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish nationally representative blood pressure reference values for children aged 5 to under 18 years in South Africa. By engaging with schools and communities, the study will collect data from a diverse sample of over 22,000 children across various regions. The goal is to develop evidence-based guidelines for managing hypertension in the pediatric population, particularly for those of African ancestry, addressing the current reliance on inappropriate international standards.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All children between ages 5-\<18 years
* All children with voluntary assent/consent and parent's permission

Exclusion Criteria:

* circumstances interfere with the participant's ability to give informed consent (diminished understanding or comprehension, or any language barriers that may pose potential risk in participation under false expectations)
* randomly selected children who choose not to participate (lack of assent/consent), even if parent's permission was received,
* conditions that interfere with a patient's ability to follow study guidelines, e.g., the use of drugs, alcohol or tobacco products
* ages \>18 years or under 5 years
* Children will be excluded from the analysis for the determination of normative reference values for blood pressure and anthropometry if taking certain concomitant medication(s) that may affect their blood pressure, or any underlying disease e.g., chronic kidney disease, chronic heart disease etc. that may raise blood pressure.

Where it's running

• Nelson Mandela Metropolitan University
  Port Elizabeth, Eastern Cape, South Africa Recruiting
• University of the Free State
  Bloemfontein, Free State, South Africa Recruiting
• University of the Witwatersrand
  Johannesburg, Gauteng, South Africa Recruiting
• Hypertension in Africa Research Team (HART), North-West University
  Potchefstroom, North West, South Africa Recruiting
• Walter Sisulu University
  Mthatha, Eastern Cape, South Africa Not yet recruiting
• University of KwaZulu-Natal
  Durban, KwaZulu-Natal, South Africa Not yet recruiting

Study contacts

• Study coordinator: Ruan Kruger, PhD
• Email: ruan.kruger@nwu.ac.za
• Phone: +27182992904

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.