Music therapy songwriting to improve university students' social connections and mental health

The Effects and Hyperscanning-Based Neural Mechanisms of Music Therapy on Social Relationships and Mental Wellness in University Students: A Randomized Controlled Trial

Not applicable Interventional The University of Hong Kong · NCT07024979

This project will try songwriting-based music therapy to see if it helps university students aged 18–40 with moderate depression, anxiety, or stress feel better and connect more with others.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 35 Years
SexFemale
SponsorThe University of Hong Kong Academic / other
Locations1 site (Hong Kong)
Trial IDNCT07024979 on ClinicalTrials.gov

What this trial studies

Participants who are university-aged adults with moderate symptoms on the DASS-21 will take part in a songwriting-based music therapy intervention administered at The University of Hong Kong. While participants engage in interactive music-making, researchers will use hyperscanning to record simultaneous brain activity from interacting individuals and measure interbrain synchronization. Clinical and self-report measures of depression, anxiety, stress, and social functioning will be collected before and after the intervention. The protocol excludes those with long-term professional music training, chronic illness on medication, prior brain trauma or surgery, or metal implants that interfere with recording.

Who should consider this trial

Good fit: Ideal candidates are university students aged 18–40 who speak Mandarin, Cantonese, or English and score at or above 'Moderate' on the DASS-21 subscales (Depression ≥14; Anxiety ≥10; Stress ≥19) without a formal mental health diagnosis.

Not a fit: Patients with severe psychiatric diagnoses, ongoing chronic illness requiring medication, extensive professional musical training (>10 consecutive years), a history of brain trauma/surgery, or metal implants/piercings that prevent hyperscanning may not benefit or be eligible.

Why it matters

Potential benefit: If successful, this approach could offer a non-drug way to reduce symptoms and strengthen social connectedness for affected university students.

How similar studies have performed: Prior research shows music therapy can improve mood and social functioning, but using hyperscanning to link interbrain synchronization directly to clinical benefit is a relatively new approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* (1) adults who aged between 18-40
* (2) without any mental diagnosis
* (3) able to speak and read Mandarin, Cantonese, or English
* (4) moderate stress or problems in academic activities, problems in interpersonal relationships, or adaptability to college life.
* (5) participants DASS-21 score \>= "Moderate" severity on each subscale (Depression \>= 14; Anxiety \>= 10; Stress \>= 19).

Exclusion Criteria:

* (1) has more than 10 consecutive years professional music training
* (2) with chronic illness and taking medication
* (3) with prior history of brain trauma or brain surgery
* (4) wearing metal piercings or implants.

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Depressive SymptomsAnxietyStress
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.