Clinical trial Recruiting at 1 site Interventional Ages 50 to 79

Music therapy for people with Parkinson's disease

Official title: Harmonization of Breathing Through Music Therapy and Its Impact on Anxiety, Quality of Life, and Autonomic Dysfunction in Parkinson's Disease

Run by Klinik Arlesheim · NCT07734181 · Data updated 2026-11-12

This study tests whether a personalized music therapy session using gentle string-playing, singing, and lyre can help reduce anxiety and improve quality of life for people with Parkinson's disease.

Quick facts

Study typeInterventional
Ages50 Years to 79 Years
SexAll
Enrollment50 (estimated)
SponsorKlinik Arlesheim
Academic / other
Locations1 site (Arlesheim, Basel-Landschaft)
StatusRecruiting
StartedJune 2, 2026
Main results expectedSeptember 1, 2028
Study endsSeptember 2, 2028
Registry record updatedJuly 30, 2026
Trial IDNCT07734181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with Parkinson's disease (Hoehn and Yahr stages 1-4) who understand German and can consent.

Probably not a fit

Individuals with severe hearing impairment, dementia, or other major somatic/psychiatric conditions may not benefit or may be unable to participate safely.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores whether individualized music therapy can ease anxiety and improve autonomic function and well-being in Parkinson's disease patients. The therapy combines slow, gentle bowing of a string instrument with the therapist's singing and lyre playing, aiming to induce relaxation and improve heart rate variability. Primary outcome is anxiety, with secondary goals including quality of life and autonomic indicators. Eligible participants have Parkinson's disease at Hoehn and Yahr stages 1-4, are fluent in German, and can provide informed consent. Exclusions include prior music therapy in the last year, severe hearing loss, dementia, or other conditions that could confound results.

Why it matters

Potential benefit: If successful, participants may experience reduced anxiety and improved quality of life and autonomic regulation.

How similar studies have gone: Previous research suggests music-based interventions can affect mood and autonomic function, but this specific anthroposophical approach in PD is exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parkinson's disease, Hoehn and Yahr stages 1-4
* good understanding of the German language
* Signed written informed consent

Exclusion Criteria:

* Previous music therapy within the last 12 months
* Severe hearing impairment
* Manifest dementia (MoCA \< 20)
* Severe physical disability
* Severe somatic or psychiatric illness
* Concurrent participation in another clinical trial targeting treatment of Parkinson's disease

Where it's running

  • Klinik Arlesheim AG
    Arlesheim, Basel-Landschaft, Switzerland
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.