Multisite upper limb surgery in children with unilateral cerebral palsy
Official title: Retrospective Study of Functional Benefits of Individualized Multisite Neuro-Orthopedic Upper Limb Surgery in Children With Unilateral Cerebral Palsy
Run by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française · NCT07891078 · Data updated 2026-11-12
This study looks at whether individualized multisite upper limb surgery helps improve hand function in kids with hemiplegic cerebral palsy, using each child as their own control before and after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 17 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française Academic / other |
| Locations | 1 site (Lyon) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | September 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT07891078 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children under 18 with unilateral upper limb involvement due to cerebral palsy who have undergone multisite neuro-orthopedic upper limb surgery at the study center and have pre- and post-operative assessments.
✕Probably not a fit
Patients without measurable post-operative improvement in hand function or with incomplete follow-up data may not see reported benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective, before-and-after study of children with unilateral cerebral palsy who underwent multisite neuro-orthopedic upper limb surgery. Functional outcomes are drawn from routine clinical data collected up to 3-5 years before and 1-2 years after surgery, with each patient serving as their own control. Primary outcome is upper limb function measured by the MA2, while secondary outcomes include unimanual dexterity, Box and Block Test performance, bimanual performance, and satisfaction. The study also seeks to identify factors that influence surgical outcomes, such as age at surgery and cognitive or sensory impairments. Approximately 70 patients operated at a single center between 2012 and 2025 are included, with emphasis on real-world clinical practice and long-term effects.
Why it matters
Potential benefit: If successful, the study could clarify the functional benefits of multisite upper limb surgery for children with unilateral CP.
How similar studies have gone: Previous systematic reviews note limited high-quality evidence for functional gains after upper limb surgery in CP, making this observational work relatively novel but contextually grounded.
Who can join: the full rules
Show full inclusion / exclusion criteria
INCLUSION CRITERIA * Minor patient (age \< 18 years at the time of the surgical project) * Unilateral upper limb involvement due to Cerebral Palsy * Having undergone neuro-orthopedic upper limb surgery * Surgery performed by the surgeon who participated in the multidisciplinary surgical planning meeting (EMC) * Surgery performed between January 1, 2012 and June 30, 2025 * Availability of at least one pre-operative assessment and one comparative post-operative assessment at more than 12 months after surgery * Followed at the CMCR des Massues NON-INCLUSION CRITERIA * Refusal of medical data processing for research purposes
Where it's running
-
Centre Médico chirurgical de Réadaptation des Massues
Lyon, France Recruiting
Study contacts
- Study coordinator: Julie Rozaire, PhD
- Email: julie.rozaire@croix-rouge.fr
- Phone: +334 72 38 11 43
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.