Multimodal-feedback vision rehabilitation for people with central vision loss
Official title: Vision Rehabilitation Training With Multimodal Feedback in Central Vision Loss
Run by New England College of Optometry · NCT07577219 · Data updated 2026-11-12
This trial will test whether five weekly sessions of binocular multimodal feedback training can improve eye movement control in people with bilateral central vision loss from macular degeneration.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 14 Years and up |
| Sex | All |
| Enrollment | 12 (estimated) |
| Sponsor | New England College of Optometry Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | January 31, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT07577219 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are age 14 or older with bilateral central scotomas from macular disease, visual acuity between 20/60 and 20/200, stable vision for the past six months, normal cognition, and adequate hearing and English fluency to complete training.
✕Probably not a fit
Patients with unstable or actively treated ocular disease, severe peripheral field restriction, other conditions that independently impair oculomotor control, significant hearing loss, or visual acuity outside the specified range are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study will enroll 8–15 participants with bilateral central vision loss from macular degeneration who will complete five weekly in-person binocular training sessions using high-speed eye tracking. Training pairs gaze-contingent scotoma awareness feedback and preferred retinal locus feedback with auditory cues while participants perform saccadic and smooth pursuit tasks to retrain peripheral viewing. Outcomes compare eye-movement control and functional performance before and after the training regimen. Participants must meet acuity, cognitive, and hearing criteria and attend sessions at the Boston site.
Why it matters
Potential benefit: If successful, the approach could improve eye movement control and make everyday tasks like reading, face recognition, and navigation easier for people with central vision loss.
How similar studies have gone: Prior pilot work showed limited immediate benefit from single-session feedback but suggested that combining visual and auditory feedback across sessions may produce improved eye-movement control.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Bilateral central scotomas confirmed via computerized tangent screen Visual acuity between 20/60 and 20/200 (0.5 - 1.00 logMAR) in either eye Stable central vision loss (no change in visual acuity \>0.2 logMAR in past 6 months) Age 14 years or older, with diagnosis of macular disease Normal cognitive function (Mini-Mental State Examination score ≥24) Ability to provide informed consent and complete study visits No major hearing loss Fluent in English Exclusion Criteria: Unstable ocular disease (e.g., ongoing treatments and/or injections) Peripheral vision loss of less than 40 degrees Conditions affecting oculomotor control independent of CVL
Where it's running
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New England College of Optometry
Boston, Massachusetts, United States Recruiting
Study contacts
- Study coordinator: Nicole C Ross, OD
- Email: rossn@neco.edu
- Phone: 6175875626
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.