Multifocal contact lenses versus single‑vision contacts plus reading glasses for presbyopia

Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasse

We will try multifocal contact lenses compared with single‑vision contact lenses plus reading glasses for people over 40 who need reading power.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 30 (estimated)
• Ages: 40 Years and up
• Sex: All
• Sponsor: Ohio State University (Academic / other)
• Locations: 1 site (Columbus, Ohio)
• Trial ID: NCT07218731 on ClinicalTrials.gov

What this trial studies

Adults aged 40 and older with presbyopia, corrected distance visual acuity of 20/25 or better, and an add power of +0.75 D or greater will be enrolled. Participants will wear multifocal contact lenses and spherical (single‑vision) contact lenses with reading glasses and report their wear experience, while investigators record clinical vision measures. The study excludes individuals with active eye infection or surface disease, prior refractive surgery, known contact lens solution allergies, or pregnancy. Outcomes will focus on patient comfort, visual satisfaction, and functional near and distance vision with each correction method.

Who should consider this trial

Good fit: Ideal candidates are adults aged 40 or older with presbyopia who have corrected distance acuity of 20/25 or better, require at least +0.75 D add, are in stable general health, and can wear contact lenses.

Not a fit: People with active ocular surface disease or infection, a history of refractive surgery, known allergies to lens solutions, pregnancy, or inability to meet the vision or add requirements are unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, this could show that multifocal contacts let many people see near and far without separate reading glasses, improving convenience and daily functioning.

How similar studies have performed: Previous studies show multifocal contact lenses can provide acceptable near and distance vision for many presbyopes, though comfort and visual quality results are variable across individuals and lens designs.

Eligibility criteria

Inclusion Criteria:

1. At least 40 years of age.
2. Ability to give informed consent.
3. Subjects must have corrected distance visual acuity in both eyes equivalent to 20/25 or better at the screening visit.
4. Require an add power of +0.75 D or greater when tested at 40cm.
5. Good general health defined by medication use that has not changed within the last 30 days and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the Investigator.

Exclusion Criteria:

1. Current or active inflammation or infection as determined by the Investigator.
2. Current eye disease, infection or inflammation that affects the surface of the eye such as but not limited to moderate or greater blepharitis and ocular allergy.
3. History of refractive surgery.
4. Known history of allergy or sensitivity to contact lens solutions and/or sodium fluorescein.
5. Is pregnant or lactating or planning a pregnancy during enrollment of the study.
6. Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable.
7. Have been diagnosed with dry eye previously
8. Has a systemic condition that in the opinion of the investigator may affect a study outcome variable.

Where this trial is running

Columbus, Ohio

• The Ohio State University College of Optometry — Columbus, Ohio, United States (Recruiting)

Study contacts

• Study coordinator: Study Coordinators

Conditions Presbyopia Correction; Presbyopia