Multi-scale spatio-temporal analysis of colorectal cancer data
Multi-scale Spatio-Temporal Analysis of Research Data
Universidad de Granada · NCT07189312
This project will test a computer framework that uses tumor and omics data from colorectal cancer patients having planned surgery to make multi-scale maps of how the disease behaves across space and time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Universidad de Granada (other) |
| Locations | 1 site (Granada, Granada) |
| Trial ID | NCT07189312 on ClinicalTrials.gov |
What this trial studies
This observational project will collect clinical and molecular data from colorectal cancer patients undergoing planned surgery and apply computational methods to build multi-scale spatio-temporal (ST) models with statistical inference. Investigators aim to integrate high-throughput omics, including single-cell and spatial measurements, to capture tumor heterogeneity and microenvironment patterns over space and time. The framework is intended as a common solution that can be adapted to different applications rather than a single-disease tool. The project is led by Universidad de Granada with clinical collaboration at Virgen de las Nieves Hospital in Granada, Spain.
Who should consider this trial
Good fit: Adults with a diagnosis of colorectal cancer who are scheduled for planned surgery, who do not have microsatellite instability, and who have no other diseases that would affect the cancer pathology are the intended participants.
Not a fit: Patients requiring urgent surgery, those with microsatellite instability, or those with significant comorbidities that affect cancer pathology are unlikely to be eligible or to benefit from this project.
Why it matters
Potential benefit: If successful, the framework could improve understanding of tumor progression and help guide more personalized treatment or surgical planning for colorectal cancer patients.
How similar studies have performed: Related single-cell and spatial omics studies have shown promise in mapping tumor biology, but a unified multi-scale spatio-temporal modeling framework of this type is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis for colorectal cancer * Patients with cancer planned surgery * Absence of instability microsatellites * Absence of any other associated disease that can affect the cancer pathology Exclusion Criteria: * Patients who need an urgent surgery
Where this trial is running
Granada, Granada
- Virgen de las Nieves Hospital — Granada, Granada, Spain (RECRUITING)
Study contacts
- Study coordinator: Jose Camacho, PhD
- Email: jcamacho@ugr.es
- Phone: +34 958248898
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colorectal Cancer