Multi-Field-Strength Brain MRI Atlas for Healthy Chinese Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective imaging study collects structural, diffusion, functional, and quantitative MRI data from healthy Chinese volunteers at multiple field strengths. Standardized protocols include preprocessing, registration, and segmentation to create multi-field-strength brain templates. The goal is to characterize field-strength–related differences in brain morphometry, diffusion metrics, and functional connectivity, and to establish normative reference data. Data will be analyzed to assess consistency across field strengths and to produce accessible brain atlas resources for researchers. Eligible participants will undergo MRI scans at 0.55T, 1.5T, 3T, 5T, and 7T with appropriate safety screenings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 16 to 66 years.
* Voluntarily participates in the study and provides written informed consent.
* No contraindications to MRI examination and able to cooperate with and complete the MRI examinations.
* Female participants must not be pregnant.
* No current or previous clinical diagnosis of severe neurological or psychiatric disorders, such as schizophrenia, dementia, epilepsy, or severe sequelae of traumatic brain injury.
* No obvious intracranial lesions or structural abnormalities identified on routine MRI examination.

Exclusion Criteria:

* Presence of contraindications to MRI examination, including MRI-incompatible implanted metallic or electronic devices, cochlear implants, cardiac pacemakers, intracranial metallic clips, or similar devices.
* Severe claustrophobia preventing completion of the MRI examination.
* Pregnancy.
* Current or previous clinical diagnosis of severe neurological or psychiatric disorders.
* History of severe head trauma, brain tumor, stroke, brain surgery, or other conditions that may substantially affect brain structure or function.
* MRI data of insufficient quality for analysis due to marked discomfort, excessive head motion, or other causes during the examination.

Where it's running

• Tangdu Hospital, Fourth Military Medical University
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Study coordinator: Ziheng Zhou
• Email: 173416171@qq.com
• Phone: +86 18710574531

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.