MRI-guided cryoablation for pain relief in the head, neck, and spine

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to alleviate pain in patients suffering from facet joint disease or nerve compression in the head and neck. It utilizes MRI-guided cryoablation, a minimally invasive technique that destroys pain-transmitting nerves to provide longer-lasting pain relief compared to traditional methods. The procedure is performed in the Advanced Multimodality Image Guided Operating Suite (AMIGO) at Brigham and Women's Hospital, which enhances precision and reduces risks associated with nerve ablation. Participants will undergo imaging and treatment to assess the efficacy of this innovative approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants must be willing and able to sign a written informed consent document.
* Patients must have facet joint disease or pain due to a damaged or compressed nerve that would benefit from a minimally invasive image-guided procedure (i.e., adjacent to critical structures, better visualized under 3 Tesla MRI than CT)
* Subjects must be able to adhere to the visit schedules and attend pre and post imaging.
* Participants must be at least 18 years of age
* Participants must have an estimated life expectancy of \>8 weeks in the opinion of the clinician.

  * Patients with radiculopathy must have the cause of pain confirmed by a nerve block within 3 months prior to ablation

Exclusion Criteria:

* Contraindications to MRI and Gadolinium- (i.e. estimated Glomerular Filtration Rate \<60ml/min, metal clips)
* Pregnant or breastfeeding woman are excluded from this research.

Where it's running

• Brigham and Women's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Thomas C Lee, MD — Brigham and Women's Hospital
• Study coordinator: Thomas Lee, MD
• Email: tchlee@partners.org
• Phone: (617) 732-7260

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.