MRI-based noninvasive detection and monitoring of oral lesions in people with Fanconi anemia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses magnetic resonance imaging (MRI) and dedicated dental MRI to explore noninvasive ways to identify oral lesions that could be cancerous or precancerous in patients with Fanconi anemia. Participants include adults with FA who consent to MRI scans and can tolerate imaging. The study aims to correlate imaging findings with clinical evaluations to see if MRI can help in monitoring oral health and guiding further diagnostics. No intervention beyond imaging is performed, and no results are provided here about specific diagnostic accuracy. The investigation is sponsored by the University of Minnesota and conducted at its Minneapolis campus.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs
* Willing to provide informed consent

Exclusion Criteria:

* Patient without diagnosis of FA
* Patients with FA who are under the age of 18
* Unable to tolerate any MRI due to claustrophobia
* Any contraindication for the MRI
* Unable to provide informed consent or comply with the study protocol

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Rachel Uppgaard — University of Minnesota
• Study coordinator: Carla Campbell, BS
• Email: camp2757@umn.edu
• Phone: 612-625-6976

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using Afatinib to treat patients with Fanconi Anemia and advanced head and neck cancer

  This study is testing if Afatinib can help people with advanced head and neck cancer who also have Fanconi Anemia feel better and improve their condition.

  Recruiting at 2 sites Phase 1/2 Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Hanover and 1 other locations · NCT06648096

• Investigating how acetaldehyde contributes to oral cancer development

  This study is trying to see how drinking alcohol affects the development of oral cancer in healthy people and those with Fanconi anemia by looking at samples like saliva and urine.

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• Understanding Squamous Cell Carcinoma in People with Fanconi Anemia

  This study looks at how squamous cell carcinoma develops in people with Fanconi anemia to help catch it early and improve treatment options.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05687149

• Transplanting depleted donor stem cells in patients with Fanconi Anemia using a new conditioning treatment

  This study is testing a new way to use donor stem cells for people with Fanconi Anemia by giving them a special treatment first to see if it helps their blood and immune system recover better and with fewer side effects.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.