Moxibustion at specific points for nighttime urination
Official title: Evaluation of the Efficacy and Safety of Acupoint Moxibustion for Nocturia: A Pilot Study
Run by Buddhist Tzu Chi General Hospital · NCT07598227 · Data updated 2026-11-12
This study tests whether applying heat to acupuncture points (moxibustion) at night can help adults 40 and older who wake up two or more times for urination.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Buddhist Tzu Chi General Hospital Academic / other |
| Locations | 1 site (Hualien City) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT07598227 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 40 years or older with two or more nocturia episodes per night.
✕Probably not a fit
Patients with active infections, poorly controlled diabetes, neurogenic bladder, severe heart failure, recent TCM therapy for nocturia, or pregnancy may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial investigates the safety and potential benefit of acupoint moxibustion for nocturia in adults aged 40 and older with frequent nighttime voiding. Researchers used patient diaries, IPSS, OABSS, QoL, and TCM-based assessments to evaluate outcomes and feasibility. The study aims to determine if moxibustion could be a cost-effective, complementary option alongside or instead of standard therapies. Eligible participants have no active UTI, well-controlled comorbidities, and are not receiving other recent TCM treatments for nocturia. The research is conducted at Buddhist Tzu Chi facilities in Hualien, Taiwan, led by Buddhist Tzu Chi General Hospital.
Why it matters
Potential benefit: If successful, patients may experience fewer nocturnal awakenings and improved quality of life.
How similar studies have gone: Previous work has explored acupoint therapies for nocturia, with mixed results and limited large-scale evidence; this study adds randomized data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 40 years or older. * Experiencing two or more nocturia episodes per night. Exclusion Criteria * Active urinary tract infection (UTI). * Poorly controlled diabetes mellitus (defined as HbA1c \> 6.5%). * Presence of a neurogenic bladder caused by conditions such as multiple sclerosis, Parkinson's disease, stroke, spinal cord injury, or nerve damage resulting from major pelvic surgery. * Severe congestive heart failure (New York Heart Association \[NYHA\] functional class \> II). * Use of other Traditional Chinese Medicine (TCM) therapies for nocturia symptoms within the past month (30 days). * Pregnant women.
Where it's running
-
Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Hualien City, Taiwan Recruiting
Study contacts
- Study coordinator: Yen-Lun Kung
- Email: kung818@gmail.com
- Phone: +886-3-8561825
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.