Clinical trial Recruiting at 3 sites Interventional Ages 12 to 19

Motivational intervention for teens at risk of alcohol and cannabis use

Official title: Effectiveness of Brief Intervention in Primary Care for Diverse Young People

Run by Rand · NCT06699251 · Data updated 2026-11-12

This study is testing a new motivational program to help teens aged 12-17 who are at risk of using alcohol and cannabis by offering them support either online or in-person.

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Quick facts

Study typeInterventional
Ages12 Years to 19 Years
SexAll
Enrollment500 (estimated)
SponsorRand
Academic / other
Locations3 sites (Commerce, California and 2 other locations)
StatusRecruiting
StartedApril 28, 2025
Main results expectedJuly 28, 2028
Study endsFebruary 28, 2029
Registry record updatedSeptember 9, 2026
Trial IDNCT06699251 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adolescents aged 12-17 who receive healthcare at participating health systems and screen positive for at-risk substance use.

Probably not a fit

Patients who do not meet the inclusion criteria or do not screen positive for risky substance use will not benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention focuses on providing a brief motivational interviewing approach to address alcohol and cannabis use among diverse adolescents aged 12-17. Teens who screen positive for risky substance use will be enrolled through partner clinics, where they will complete an online consent process and baseline survey. Based on their responses, participants will receive either enhanced usual care or the Chat intervention, which can be delivered virtually or in-person. Follow-up surveys will be conducted at 3, 6, and 12 months, with participants receiving gift card incentives for their participation.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce risky alcohol and cannabis use among adolescents.

How similar studies have gone: Previous studies have shown that brief interventions can be effective in reducing substance use among adolescents, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* receive health care at one of two participating health systems
* aged 12-17
* screen positive for being at risk for alcohol or cannabis use using the CRAFFT

Exclusion Criteria:

* if they don't meet the inclusion criteria, they will be excluded

Where it's running

  • AltaMed Health Services
    Commerce, California, United States
    Recruiting
  • Valley Community Healthcare
    North Hollywood, California, United States
    Recruiting
  • University of Pittsburgh Medical Center Children's Hospital
    Pittsburgh, Pennsylvania, United States
    Recruiting

Study contacts

  • Principal investigator: Elizabeth J. D'Amico, PhD — Rand
  • Study coordinator: Elizabeth J D'Amico, PhD
  • Email: damico@rand.org
  • Phone: 3103930411

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.