Monitoring vital signs in newborns to improve care

Neo-vital: Investigating Changes in Vital Signs in Neonates

Observational University of Oxford · NCT06032494

This study looks at how different treatments affect the vital signs of newborns in a neonatal care unit to help doctors create better, personalized care plans for each baby.

Quick facts

Study typeObservational
Enrollment200 (estimated)
AgesN/A to 42 Weeks
SexAll
SponsorUniversity of Oxford Academic / other
Locations1 site (Oxford)
Trial IDNCT06032494 on ClinicalTrials.gov

What this trial studies

This observational study focuses on understanding how various medical procedures and medications affect the vital signs of newborns in a neonatal care unit. By continuously monitoring heart rate, respiration, and oxygen saturation, the study aims to identify patterns in how different infants respond to treatments. The goal is to develop predictive models that can help healthcare providers tailor individualized care plans based on each infant's baseline vital signs. This approach could enhance the safety and effectiveness of treatments administered to vulnerable newborns.

Who should consider this trial

Good fit: Ideal candidates for this study are infants born to mothers aged 16 or over who are admitted to the Newborn Care Unit at John Radcliffe Hospital.

Not a fit: Infants with known chromosomal abnormalities or life-threatening congenital conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and safer treatment options for newborns requiring neonatal care.

How similar studies have performed: While this approach is observational and builds on existing practices, similar studies have shown promise in improving individualized care in neonatal settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Infants will be eligible to be included in the study if they are:

* Born to, or expected to be born to, a mother aged 16 or over
* Admitted to the Newborn Care Unit, John Radcliffe Hospital, or anticipated delivery of a baby who will require admittance to the Newborn Care Unit at birth
* Mother given informed written consent

Exclusion Criteria:

Infants will be ineligible if the following exclusion criteria applies:

• Known chromosomal abnormality or life-threatening congenital abnormality

Where this trial is running

Oxford

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions InfantNewbornpretermrespirationoxygen saturationheart rate
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.