Monitoring ventilation distribution in children with respiratory failure using electrical impedance tomography
Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure: Impact of Intervention
This study is testing a new way to monitor how well children with breathing problems are getting air in their lungs to see how different treatments can help them breathe better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 4 sites (Bron, Rhone and 3 other locations) |
| Trial ID | NCT05347563 on ClinicalTrials.gov |
What this trial studies
This observational study aims to utilize electrical impedance tomography (EIT) to monitor and describe the regional distribution of ventilation in children suffering from acute respiratory failure in the pediatric intensive care unit (PICU). The study will assess how various interventions, such as changes in ventilatory settings, positioning, suctioning, and respiratory kinesiotherapy, impact ventilation distribution. By providing continuous, real-time data, the study seeks to enhance understanding of respiratory management in critically ill children. The findings may help inform clinical practices in pediatric respiratory care.
Who should consider this trial
Good fit: Ideal candidates for this study are children under 18 years old who are admitted to the PICU with acute respiratory failure and are monitored using EIT.
Not a fit: Patients who may not benefit from this study include those without access to the EIT monitoring system or those with contraindications to the use of a thoracic belt.
Why it matters
Potential benefit: If successful, this study could improve ventilation management strategies for children with acute respiratory failure, potentially leading to better patient outcomes.
How similar studies have performed: While there is limited data on the use of EIT in pediatric populations, similar approaches in adult patients have shown promise, indicating potential for success in this novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Groupe A * children \< 18 years * Admitted to the PICU with acute respiratory failure * Monitoring with EIT * non opposition of parents or legal representative Groupe B * children \< 18 years * With general anesthesia and mechanical ventilation * Monitoring with EIT * non opposition of parents or legal representative Exclusion Criteria: * Monitor not available * contra indication to the use of thoracic belt * Intraoperative period with use of electrocautery * Child not affiliated to a social security system and under protective measures legal
Where this trial is running
Bron, Rhone and 3 other locations
- Hôpital Femme Mère Enfant Service de néonatologie et réanimation néonatale — Bron, Rhone, France (Recruiting)
- Hôpital Femme Mère Enfant Service de réanimation et d'urgence pédiatrique — Bron, Rhone, France (Recruiting)
- Paediatric intensive care Unit — Bron, Rhone, France (Recruiting)
- Hôpital Louis Pradel GHE - Réanimation Cardiaque Pédiatrique (U11) — Bron, Rhone, France (Recruiting)
Study contacts
- Principal investigator: Florent Baudin, MD — Hospices Civils de Lyon
- Study coordinator: Florent Baudin, MD
- Email: florent.baudin@chu-lyon.fr
- Phone: 04 72 12 97 05
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.