Monitoring ventilation distribution in children with respiratory failure using electrical impedance tomography
Official title: Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure: Impact of Intervention
Run by Hospices Civils de Lyon · NCT05347563 · Data updated 2026-11-12
This study is testing a new way to monitor how well children with breathing problems are getting air in their lungs to see how different treatments can help them breathe better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years to 18 Years |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 4 sites (Bron, Rhone and 3 other locations) |
| Status | Recruiting |
| Started | June 18, 2022 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | January 23, 2026 |
| Trial ID | NCT05347563 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children under 18 years old who are admitted to the PICU with acute respiratory failure and are monitored using EIT.
✕Probably not a fit
Patients who may not benefit from this study include those without access to the EIT monitoring system or those with contraindications to the use of a thoracic belt.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to utilize electrical impedance tomography (EIT) to monitor and describe the regional distribution of ventilation in children suffering from acute respiratory failure in the pediatric intensive care unit (PICU). The study will assess how various interventions, such as changes in ventilatory settings, positioning, suctioning, and respiratory kinesiotherapy, impact ventilation distribution. By providing continuous, real-time data, the study seeks to enhance understanding of respiratory management in critically ill children. The findings may help inform clinical practices in pediatric respiratory care.
Why it matters
Potential benefit: If successful, this study could improve ventilation management strategies for children with acute respiratory failure, potentially leading to better patient outcomes.
How similar studies have gone: While there is limited data on the use of EIT in pediatric populations, similar approaches in adult patients have shown promise, indicating potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Groupe A * children \< 18 years * Admitted to the PICU with acute respiratory failure * Monitoring with EIT * non opposition of parents or legal representative Groupe B * children \< 18 years * With general anesthesia and mechanical ventilation * Monitoring with EIT * non opposition of parents or legal representative Exclusion Criteria: * Monitor not available * contra indication to the use of thoracic belt * Intraoperative period with use of electrocautery * Child not affiliated to a social security system and under protective measures legal
Where it's running
-
Hôpital Femme Mère Enfant Service de néonatologie et réanimation néonatale
Bron, Rhone, France Recruiting -
Hôpital Femme Mère Enfant Service de réanimation et d'urgence pédiatrique
Bron, Rhone, France Recruiting -
Paediatric intensive care Unit
Bron, Rhone, France Recruiting -
Hôpital Louis Pradel GHE - Réanimation Cardiaque Pédiatrique (U11)
Bron, Rhone, France Recruiting
Study contacts
- Principal investigator: Florent Baudin, MD — Hospices Civils de Lyon
- Study coordinator: Florent Baudin, MD
- Email: florent.baudin@chu-lyon.fr
- Phone: 04 72 12 97 05
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.