Monitoring side effects of radiotherapy in metastatic cancer patients using wearable technology

Patient Reported Outcomes/Metrics Program Trial - Palliative Radiation

Observational University Health Network, Toronto · NCT04983199

This study is testing if a wearable device can help track vital signs and activity levels in patients with metastatic cancer undergoing radiotherapy to better manage side effects and improve their care.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Health Network, Toronto Academic / other
Locations1 site (Toronto, Ontario)
Trial IDNCT04983199 on ClinicalTrials.gov

What this trial studies

This observational study aims to recruit 100 patients undergoing palliative radiotherapy for metastatic cancer to wear the Hexoskin Medical System. The study will assess the feasibility of using this wearable technology to monitor vital signs and activity levels, which may help in the early detection and management of radiotherapy-related side effects. By combining objective data with patient-reported outcomes, the study seeks to enhance the evaluation of treatment effects and improve patient care. Participants will also complete questionnaires to provide insights into their quality of life and pain management.

Who should consider this trial

Good fit: Ideal candidates include patients with a known cancer diagnosis who are scheduled to receive palliative radiotherapy and can use the Hexoskin Medical Shirt.

Not a fit: Patients receiving whole brain radiotherapy, those with major cognitive impairments, or those with certain medical devices like pacemakers may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved monitoring and management of side effects from radiotherapy, enhancing the quality of life for patients with metastatic cancer.

How similar studies have performed: While the use of wearable technology in monitoring health outcomes is gaining traction, this specific approach in the context of palliative radiotherapy is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Planned to receive palliative radiotherapy for pain
* Known cancer diagnosis
* Able to wear Hexoskin Medical Shirt
* Ability to use and populate the mobile app (Zamplo) with or without assistance
* ECOG: 0-3
* Willing to provide a list of analgesic (pain relief) medication
* Willing to complete questionnaires
* Life expectancy of at least 3 months

Exclusion Criteria:

* Receiving whole brain radiotherapy
* Major cognitive or psychiatric impairments
* Pregnant women
* Allergies to: polyester, synthetic fibers
* Patients with pacemakers or implantable cardioverter-defibrillator (ICD)
* Patients on a Holter Monitor

Where this trial is running

Toronto, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Metastatic CancerPalliative
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.