Monitoring quality of life in lung cancer patients using electronic tools

Impact of Routine Electronic Monitoring of Health-related Quality of Life on Care Relationship of Cancer Patients With Non-small Cell Lung Cancer, Locally Advanced or Metastatic, Systemic Treatment-naïve: a Randomized Trial

Centre Hospitalier Universitaire de Besancon · NCT04857970

This study tests if using electronic health questionnaires to check on quality of life helps doctors provide better care for patients with advanced lung cancer who haven't started treatment yet.

Quick facts

Study typeObservational
Enrollment72 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Besancon (other)
Locations1 site (Besançon)
Trial IDNCT04857970 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of routine electronic monitoring of health-related quality of life (HRQoL) in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who have not received systemic treatment. Patients will be randomized into two groups: one receiving HRQoL questionnaires electronically with results shared with their physicians, and the other completing paper-based questionnaires without feedback to their doctors. The study aims to assess how this electronic monitoring affects the care relationship and patient outcomes over four encounters. Additionally, a sub-cohort will participate in semi-structured interviews to explore their experiences further.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older diagnosed with locally advanced or metastatic non-small cell lung cancer who have not undergone prior systemic therapy.

Not a fit: Patients with tumor recurrence or those receiving oral antineoplastic therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance personalized care and improve the quality of life for lung cancer patients.

How similar studies have performed: Other studies have shown promise in using electronic monitoring for patient-reported outcomes, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria for patients:

* Any patient diagnosed with locally advanced or metastatic non-small cell lung cancer
* Patients treated at University Hospital of Besançon
* No prior systemic therapy for cancer
* Males and Females, age ≥18 years old
* Patient able to complete the HRQoL questionnaires
* Patients who gave their informed consent to participate.

Inclusion Criteria for the sub cohort of patients undergoing the semi-structured interview with the researcher in psychology:

* Patients who realized 4 clinical encounters with collection of HRQoL
* For patients from experimental arm, the physician must have checked HRQoL results

Inclusion Criteria for physicians:

• Any physician treating patients included in the study REMOQOL-Poumon

Exclusion Criteria:

* Patients with tumor recurrence
* Patients receiving oral antineoplastic therapy for whom at least monthly follow-up is not feasible
* Patients with psychopathology or serious cognitive problems

Where this trial is running

Besançon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Lung Cancer, Non Small Cell Lung Cancer, Cancer, Health-related quality of life, E-health, Patient-reported outcome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.