Monitoring patients with Premature Ventricular Contractions using implantable loop recorders
Official title: Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions
Run by Kansas City Heart Rhythm Research Foundation · NCT06060548 · Data updated 2026-11-12
This study is testing how well implantable loop recorders can help track heart rhythms in people with Premature Ventricular Contractions to better understand their condition over a year.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Kansas City Heart Rhythm Research Foundation Academic / other |
| Locations | 6 sites (Overland Park, Kansas and 5 other locations) |
| Status | Recruiting |
| Started | April 20, 2022 |
| Main results expected | September 2025 |
| Study ends | December 2025 |
| Registry record updated | August 28, 2025 |
| Trial ID | NCT06060548 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who have a Medtronic LINQ II ILR and can provide informed consent.
✕Probably not a fit
Patients with a history of myocardial infarction, significant coronary artery disease, or existing implantable defibrillators may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Approximately 50 patients will be monitored over a 12-month period using implantable loop recorders (ILRs) to assess the incidence of cardiac arrhythmias. The study will also evaluate clinical, biomarker, and radiological evidence of myocarditis in this cohort to understand its association with arrhythmias and the role of ILRs in patient management.
Why it matters
Potential benefit: If successful, this study could improve the management of patients with PVCs and enhance understanding of associated cardiac conditions.
How similar studies have gone: While this approach is observational, similar studies using ILRs for monitoring arrhythmias have shown promise in other populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \> 18 years of age * Have a Medtronic LINQ II ILR * Willing and able to give written informed consent Exclusion Criteria: * History of myocardial infarction * Significant flow-limiting coronary artery disease (≥50% stenosis) on invasive coronary angiography or Computed tomography angiography (CTA). * History of cardiac arrest * With existing implantable defibrillators * Currently pregnant
Where it's running
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Kansas City Heart Rhythm Institute - Roe Clinic
Overland Park, Kansas, United States Recruiting -
Overland Park Regional Medical Center
Overland Park, Kansas, United States Recruiting -
Centerpoint Medical Center Clinic
Independence, Missouri, United States Recruiting -
Centerpoint Medical Center
Independence, Missouri, United States Recruiting -
Research Medical Center Clinic
Kansas City, Missouri, United States Recruiting -
Research Medical Center
Kansas City, Missouri, United States Recruiting
Study contacts
- Principal investigator: Dhanunjaya Lakkireddy, MD — Kansas City Heart Rhythm Institute
- Study coordinator: Donita Atkins
- Email: datkins@kchrf.com
- Phone: 816-651-1969
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.