Monitoring patients with Premature Ventricular Contractions using implantable loop recorders
Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions
This study is testing how well implantable loop recorders can help track heart rhythms in people with Premature Ventricular Contractions to better understand their condition over a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Kansas City Heart Rhythm Research Foundation Academic / other |
| Locations | 6 sites (Overland Park, Kansas and 5 other locations) |
| Trial ID | NCT06060548 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Approximately 50 patients will be monitored over a 12-month period using implantable loop recorders (ILRs) to assess the incidence of cardiac arrhythmias. The study will also evaluate clinical, biomarker, and radiological evidence of myocarditis in this cohort to understand its association with arrhythmias and the role of ILRs in patient management.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have a Medtronic LINQ II ILR and can provide informed consent.
Not a fit: Patients with a history of myocardial infarction, significant coronary artery disease, or existing implantable defibrillators may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management of patients with PVCs and enhance understanding of associated cardiac conditions.
How similar studies have performed: While this approach is observational, similar studies using ILRs for monitoring arrhythmias have shown promise in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \> 18 years of age * Have a Medtronic LINQ II ILR * Willing and able to give written informed consent Exclusion Criteria: * History of myocardial infarction * Significant flow-limiting coronary artery disease (≥50% stenosis) on invasive coronary angiography or Computed tomography angiography (CTA). * History of cardiac arrest * With existing implantable defibrillators * Currently pregnant
Where this trial is running
Overland Park, Kansas and 5 other locations
- Kansas City Heart Rhythm Institute - Roe Clinic — Overland Park, Kansas, United States (Recruiting)
- Overland Park Regional Medical Center — Overland Park, Kansas, United States (Recruiting)
- Centerpoint Medical Center Clinic — Independence, Missouri, United States (Recruiting)
- Centerpoint Medical Center — Independence, Missouri, United States (Recruiting)
- Research Medical Center Clinic — Kansas City, Missouri, United States (Recruiting)
- Research Medical Center — Kansas City, Missouri, United States (Recruiting)
Study contacts
- Principal investigator: Dhanunjaya Lakkireddy, MD — Kansas City Heart Rhythm Institute
- Study coordinator: Donita Atkins
- Email: datkins@kchrf.com
- Phone: 816-651-1969
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.