Monitoring pain levels during regional anesthesia for upper limb surgery

Is the Regional Anesthesia Technique Painful? an Evaluation Using the Nociception Index Level (NOL), a New Pain Monitoring, and Algiscore, a Multidimensional Pain Score

Observational American Hospital of Paris · NCT06300606

This study is testing how well different methods can measure pain in adults having upper limb surgery with regional anesthesia to see if they need less sedation during the procedure.

Quick facts

Study typeObservational
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorAmerican Hospital of Paris Academic / other
Locations1 site (Neuilly-sur-Seine)
Trial IDNCT06300606 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate pain levels using the Nociception Level index (NOL) during locoregional anesthesia in patients undergoing orthopedic surgery of the upper limb. It includes 50 adult patients who will be monitored for pain through various parameters, including the NOL index, ALGISCORE, and a numerical scale. The study also assesses the requirement for sedatives like midazolam and propofol during the procedure. The monitoring starts with the initiation of venous infusion and continues through key surgical milestones.

Who should consider this trial

Good fit: Ideal candidates are adults scheduled for orthopedic surgery of the upper limb requiring locoregional anesthesia.

Not a fit: Patients under 18 years old, those requiring emergency surgery, or those refusing regional anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance pain management strategies during regional anesthesia, leading to improved patient comfort and outcomes.

How similar studies have performed: While the use of NOL monitoring has been explored in general anesthesia, this specific application in locoregional anesthesia is relatively novel and has limited prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

scheduled upper limb orthopedic surgery under regional anesthesia

Exclusion Criteria:

Patient less than 18 years old emergency surgery patient refusal of regional anesthesia chronic neurocognitive disease

Where this trial is running

Neuilly-sur-Seine

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Regional AnesthesiaPainIntraoperative Monitoringnociceptionregional anesthesiaintraoperative monitoringNOL monitor
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.