Monitoring menstrual health through hormone measurement

Quantitative Hormonal Biomarkers of Menstrual Health in Normal and Abnormal Cycles

Observational Quanovate Tech Inc. · NCT05936840

This study is testing if tracking hormone levels in urine can help understand ovulation patterns in women with regular and irregular menstrual cycles, including those with PCOS and athletes.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years to 55 Years
SexFemale
SponsorQuanovate Tech Inc. Industry-sponsored
Locations1 site (Calgary, Alberta)
Trial IDNCT05936840 on ClinicalTrials.gov

What this trial studies

The Quantum Menstrual Health Monitoring Study aims to measure four key reproductive hormones in urine to identify patterns that predict and confirm ovulation. This observational study will compare hormonal data from participants with regular menstrual cycles to those with irregular cycles, such as individuals with polycystic ovary syndrome (PCOS) and athletes. Participants will track their menstrual cycles, vital signs, and sleep patterns, which will be correlated with hormonal changes and ultrasound-confirmed ovulation. The study will utilize the Mira Monitor for hormone tracking.

Who should consider this trial

Good fit: Ideal candidates include regularly menstruating women aged 18-45, those with PCOS, or athletes who meet specific inclusion criteria.

Not a fit: Patients with known conditions that impair ovulation or fertility, such as endometriosis or those currently pregnant, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into menstrual health and improve ovulation prediction for women with irregular cycles.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in understanding hormonal patterns related to menstrual health.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Regularly menstruating, PCOS or athlete participants aged 18-45
* Negative pregnancy test at the beginning and at the end of each cycle
* Cycle lengths 24-34 days
* Knowledge of previous 3 cycle lengths
* Able to travel to Calgary Clinic for regular ultrasounds during the study period

Exclusion Criteria:

* For regular cycles

  * Anovulation in the last 3 cycles
  * Currently or in the previous 3 months, on medications that are known to impair or stimulate ovulation (e.g. oral contraceptives, ovulation stimulants, etc)
  * Known conditions that impair ovulation or fertility: polycystic ovarian syndrome, endometriosis, pelvic inflammatory disease in the last year, pituitary adenomas, exclusively breastfeeding
  * Previous surgeries impacting the menstrual cycle: hysterectomy, bilateral oophorectomy
  * Currently pregnant
* For PCOS and athlete groups:

  * Currently or in the previous 3 months, on medications that are known to impair or stimulate ovulation (e.g. oral contraceptives, ovulation stimulants, etc)
  * Known conditions that impair ovulation or fertility: pelvic inflammatory disease in the last year, pituitary adenomas, exclusive breastfeeding
  * Previous surgeries impacting the menstrual cycle: hysterectomy, bilateral oophorectomy
  * Currently pregnant

Where this trial is running

Calgary, Alberta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Menstrual Cycle AbnormalPolycystic Ovary SyndromeAthletesQuantitative urinary hormonesFollicle-stimulating hormoneLuteinizing hormoneEstrone-3-glucuronidePregnanediol glucuronide
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.